PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7506195-0	1993	Nimesulide inhibits platelet-activating factor synthesis in activated human neutrophils.	nimesulide	0-10	PCNA clamp associated factor	Homo sapiens	20-46	
8595070-2	1995	Recent studies indicate that nimesulide not only inhibits prostaglandin synthesis in certain cell types, but also has pleiotropic effects on neutrophil functions, including the respiratory burst, integrin-mediated adherence and synthesis of platelet-activating factor (PAF).	nimesulide	29-39	PCNA clamp associated factor	Homo sapiens	241-267	
8595070-2	1995	Recent studies indicate that nimesulide not only inhibits prostaglandin synthesis in certain cell types, but also has pleiotropic effects on neutrophil functions, including the respiratory burst, integrin-mediated adherence and synthesis of platelet-activating factor (PAF).	nimesulide	29-39	PCNA clamp associated factor	Homo sapiens	269-272	
8595070-3	1995	In the present study, the effect of nimesulide on PAF synthesis was compared with its effect on the production of leukotriene B4 (LTB4).	nimesulide	36-46	PCNA clamp associated factor	Homo sapiens	50-53	
8595070-8	1995	Furthermore, the inhibitory effects of nimesulide on PAF and LTB4 production could largely be prevented by addition of H89, an inhibitor of cAMP-dependent protein kinase (PK-A).	nimesulide	39-49	PCNA clamp associated factor	Homo sapiens	53-56	
8595070-9	1995	It is concluded that an increase in intracellular cAMP is instrumental in the observed effects of nimesulide on the release of PAF and LTB4 by activated neutrophils and that limited availability of arachidonic acid, also the substrate for the cyclooxygenase pathway, may very well contribute to the effects of nimesulide on prostaglandin synthesis observed in other cell types.	nimesulide	98-108	PCNA clamp associated factor	Homo sapiens	127-130	
7506195-7	1993	We also observed a strong inhibition of platelet-activating factor (PAF) synthesis by activated neutrophils in the presence of nimesulide.	nimesulide	127-137	PCNA clamp associated factor	Homo sapiens	40-66	
7506195-7	1993	We also observed a strong inhibition of platelet-activating factor (PAF) synthesis by activated neutrophils in the presence of nimesulide.	nimesulide	127-137	PCNA clamp associated factor	Homo sapiens	68-71