PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22980656-8 2012 Moreover, nimesulide promoted the cleavage of caspase-9 and PARP and inhibited the mRNA and protein expression of HSP70. nimesulide 11-21 caspase 9 Homo sapiens 47-56 19360361-5 2009 In addition, z-IETD-fmk, a selective caspase-8 inhibitor, suppressed the nimesulide- and radiation-induced cleavage activation of caspase-9, caspase-3, caspase-8, and Bid, and suppressed the concomitant apoptosis, indicating that the nimesulide-induced increase in radiosensitivity was initiated by caspase-8. nimesulide 234-244 caspase 9 Homo sapiens 130-139 19360361-3 2009 The combined nimesulide-radiation treatment increased apoptosis, induced the cleavage of caspase-3, caspase-9, and poly(ADP-ribose) polymerase (PARP), activated caspase-8, and induced cleavage of Bid. nimesulide 13-23 caspase 9 Homo sapiens 100-109 19360361-5 2009 In addition, z-IETD-fmk, a selective caspase-8 inhibitor, suppressed the nimesulide- and radiation-induced cleavage activation of caspase-9, caspase-3, caspase-8, and Bid, and suppressed the concomitant apoptosis, indicating that the nimesulide-induced increase in radiosensitivity was initiated by caspase-8. nimesulide 73-83 caspase 9 Homo sapiens 130-139