PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23080159-3 2012 The transient receptor potential vanilloid 1 (TRPV1) ion channel has been implicated in thermoregulation (Caterina et al., Science 288:306-313, 2000) and recently shown to exert a tonic effect on Tb in human subjects (Gavva et al., Pain 136:202-210, 2008). Terbium 196-198 transient receptor potential cation channel subfamily V member 1 Homo sapiens 4-44 23080159-3 2012 The transient receptor potential vanilloid 1 (TRPV1) ion channel has been implicated in thermoregulation (Caterina et al., Science 288:306-313, 2000) and recently shown to exert a tonic effect on Tb in human subjects (Gavva et al., Pain 136:202-210, 2008). Terbium 196-198 transient receptor potential cation channel subfamily V member 1 Homo sapiens 46-51 23080159-4 2012 We review herein the hypothesis that TRPV1 modulates the Tb response to hypoxia. Terbium 57-59 transient receptor potential cation channel subfamily V member 1 Homo sapiens 37-42 31926897-1 2020 Antagonists of the transient receptor potential vanilloid-1 (TRPV1) channel alter body temperature (Tb) in laboratory animals and humans: most cause hyperthermia; some produce hypothermia; and yet others have no effect. Terbium 100-102 transient receptor potential cation channel subfamily V member 1 Homo sapiens 19-59 31926897-1 2020 Antagonists of the transient receptor potential vanilloid-1 (TRPV1) channel alter body temperature (Tb) in laboratory animals and humans: most cause hyperthermia; some produce hypothermia; and yet others have no effect. Terbium 100-102 transient receptor potential cation channel subfamily V member 1 Homo sapiens 61-66 31926897-7 2020 A Tb response occurs when a TRPV1 antagonist blocks (in case of hyperthermia) or potentiates (hypothermia) the tonic TRPV1 activation by protons somewhere in the trunk, perhaps in muscles, and - via the acido-antithermogenic and acido-antivasoconstrictor reflexes - modulates thermogenesis and skin vasoconstriction. Terbium 2-4 transient receptor potential cation channel subfamily V member 1 Homo sapiens 28-33 31926897-7 2020 A Tb response occurs when a TRPV1 antagonist blocks (in case of hyperthermia) or potentiates (hypothermia) the tonic TRPV1 activation by protons somewhere in the trunk, perhaps in muscles, and - via the acido-antithermogenic and acido-antivasoconstrictor reflexes - modulates thermogenesis and skin vasoconstriction. Terbium 2-4 transient receptor potential cation channel subfamily V member 1 Homo sapiens 117-122 31926897-8 2020 In this work, we used a mathematical model to analyze Tb data from human clinical trials of TRPV1 antagonists. Terbium 54-56 transient receptor potential cation channel subfamily V member 1 Homo sapiens 92-97 31926897-12 2020 We also conducted a meta-analysis of Tb data from human trials and found that polymodal TRPV1 antagonists (ABT-102, AZD1386, and V116517) increase Tb, whereas the mode-selective blocker NEO6860 does not. Terbium 147-149 transient receptor potential cation channel subfamily V member 1 Homo sapiens 88-93