PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33440261-4 2021 METHODS: In the IDEA-TB study we enrolled HIV + adult patients attending 3 DREAM Centers in Kenya who were suspected of having TB. Terbium 127-129 potassium voltage-gated channel interacting protein 3 Homo sapiens 75-80 26901070-5 2016 Here, we show that the fluorescence emission and excitation spectra of the calcium luminescent analogue, Tb(3+), are enhanced upon binding to the EF-hands of DREAM due to a mechanism of energy transfer between Trp and Tb(3+). Terbium 105-107 potassium voltage-gated channel interacting protein 3 Homo sapiens 158-163 26901070-5 2016 Here, we show that the fluorescence emission and excitation spectra of the calcium luminescent analogue, Tb(3+), are enhanced upon binding to the EF-hands of DREAM due to a mechanism of energy transfer between Trp and Tb(3+). Terbium 218-220 potassium voltage-gated channel interacting protein 3 Homo sapiens 158-163 26901070-6 2016 We also observe that unlike Tb(3+)-bound calmodulin, the luminescence lifetime of terbium bound to DREAM decays as a complex multiexponential (tauaverage ~ 1.8 ms) that is sensitive to perturbation of the protein structure and drug (NS5806) binding. Terbium 82-89 potassium voltage-gated channel interacting protein 3 Homo sapiens 99-104 26901070-10 2016 Secondary structural analyses using far-UV circular dichroism and trapped ion mobility spectrometry-mass spectrometry reveal that replacement of Ca(2+) with Tb(3+) preserves the folding state with minimal changes to the overall structure of DREAM. Terbium 157-159 potassium voltage-gated channel interacting protein 3 Homo sapiens 241-246