PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
3123604-3	1987	MPTP is oxidised to its neurotoxic metabolite, 1-methyl-4-phenylpyridinium (MPP+) by monoamine oxidase B (MAO B).	1-Methyl-4-phenylpyridinium	47-74	monoamine oxidase B	Rattus norvegicus	85-104	
8121637-2	1993	Displacement of the [3H]pargyline binding on MAO-A (L(-)-deprenyl suppressed binding to MAO-B) by harman, 1-methyl-4-phenylpyridinium (MPP+) and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) revealed IC50 values of 250 +/- 100 nM, 3.1 +/- 0.8 microM, and 5.1 +/- 0.4 microM, respectively.	1-Methyl-4-phenylpyridinium	106-133	monoamine oxidase B	Rattus norvegicus	88-93	
3496045-1	1987	MPTP (1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is converted by monoamine oxidase B to its putative toxic metabolite MPP+ (1-methyl-4-phenylpyridinium ion) via MPDP+ (1-methyl-4-phenyl-2,3-dihydropyridinium ion).	1-Methyl-4-phenylpyridinium	127-154	monoamine oxidase B	Rattus norvegicus	68-87	
3123604-3	1987	MPTP is oxidised to its neurotoxic metabolite, 1-methyl-4-phenylpyridinium (MPP+) by monoamine oxidase B (MAO B).	1-Methyl-4-phenylpyridinium	47-74	monoamine oxidase B	Rattus norvegicus	106-111	
3487052-2	1986	Conversion of MPTP to 1-methyl-4-phenylpyridine (MPP+) by monoamine oxidase-B (MAO-B) appears necessary for this neurotoxicity.	1-Methyl-4-phenylpyridinium	22-47	monoamine oxidase B	Rattus norvegicus	58-77	
3487052-2	1986	Conversion of MPTP to 1-methyl-4-phenylpyridine (MPP+) by monoamine oxidase-B (MAO-B) appears necessary for this neurotoxicity.	1-Methyl-4-phenylpyridinium	22-47	monoamine oxidase B	Rattus norvegicus	79-84	
3872460-2	1985	N-Methyl-4-phenylpyridine (MPP+), a metabolite of MPTP formed by monoamine oxidase B, is accumulated into striatal and cerebral cortical synaptosomes by the dopamine and norepinephrine uptake systems, respectively, whereas MPTP itself is not accumulated.	1-Methyl-4-phenylpyridinium	0-25	monoamine oxidase B	Rattus norvegicus	65-84	
6332989-5	1984	Moreover, in rat brain preparations, the monoamine oxidase (MAO) inhibitor pargyline and the specific MAO-B inhibitor deprenil can prevent the formation of 1-methyl-4-phenyl-pyridine from MPTP, while the specific MAO-A inhibitor clorgyline has no such effect, suggesting that MAO, and specifically MAO-B, is responsible for the oxidative metabolism of MPTP.	1-Methyl-4-phenylpyridinium	156-182	monoamine oxidase B	Rattus norvegicus	102-107	
6332989-5	1984	Moreover, in rat brain preparations, the monoamine oxidase (MAO) inhibitor pargyline and the specific MAO-B inhibitor deprenil can prevent the formation of 1-methyl-4-phenyl-pyridine from MPTP, while the specific MAO-A inhibitor clorgyline has no such effect, suggesting that MAO, and specifically MAO-B, is responsible for the oxidative metabolism of MPTP.	1-Methyl-4-phenylpyridinium	156-182	monoamine oxidase B	Rattus norvegicus	298-303