PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10208303-7 1999 In addition, replacement of the 8-hydroxycarbostyril nucleus of 11a with catechol reduced the affinity of the compound for the beta2AR by 48-fold and increased its k(off). catechol 73-81 beta-2 adrenergic receptor Mesocricetus auratus 127-134