PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28130615-0	2017	Age-dependent changes of cerebral copper metabolism in Atp7b -/- knockout mouse model of Wilson"s disease by [64Cu]CuCl2-PET/CT.	cupric chloride	115-120	ATPase, Cu++ transporting, beta polypeptide	Mus musculus	55-60	
28130615-4	2017	The objective of this study was to explore the feasibility and use of copper-64 chloride ([64C]CuCl2) as a tracer for noninvasive assessment of age-dependent changes of cerebral copper metabolism in WD using an Atp7b -/- knockout mouse model of WD and positron emission tomography/computed tomography (PET/CT) imaging.	cupric chloride	95-100	ATPase, Cu++ transporting, beta polypeptide	Mus musculus	211-216	
28130615-5	2017	Continuing from our recent study of biodistribution and radiation dosimetry of [64C]CuCl2 in Atp7b -/- knockout mice, PET quantitative analysis revealed low 64Cu radioactivity in the brains of Atp7b -/- knockout mice at 7th weeks of age, compared with 64Cu radioactivity in the brains of age- and gender-matched wild type C57BL/6 mice, at 24 h (h) post intravenous injection of [64C]CuCl2 as a tracer.	cupric chloride	383-388	ATPase, Cu++ transporting, beta polypeptide	Mus musculus	193-198	
28130615-6	2017	Furthermore, age-dependent increase of 64Cu radioactivity was detected in the brains of Atp7b -/- knockout mice from the 13th to 21th weeks of age, based on the data derived from a longitudinal [64C]CuCl2-PET/CT study of Atp7b -/- knockout mice with orally administered [64Cu]CuCl2 as a tracer.	cupric chloride	199-204	ATPase, Cu++ transporting, beta polypeptide	Mus musculus	88-93	
28130615-6	2017	Furthermore, age-dependent increase of 64Cu radioactivity was detected in the brains of Atp7b -/- knockout mice from the 13th to 21th weeks of age, based on the data derived from a longitudinal [64C]CuCl2-PET/CT study of Atp7b -/- knockout mice with orally administered [64Cu]CuCl2 as a tracer.	cupric chloride	276-281	ATPase, Cu++ transporting, beta polypeptide	Mus musculus	88-93	
22170165-5	2012	RESULTS: PET-CT analysis demonstrated higher (64)Cu radioactivity in the liver of Atp7b                            (-/-) knockout mice compared with that in the control C57BL WT mice (p < 0.001), following oral administration of (64)CuCl(2) as a tracer.	cupric chloride	233-240	ATPase, Cu++ transporting, beta polypeptide	Mus musculus	82-87	
22170165-12	2012	CONCLUSIONS: PET-CT quantitative analysis demonstrated an increased level of (64)Cu radioactivity in the liver of Atp7b                            (-/-) KO mice compared with that in the control C57BL WT mice, following oral administration of (64)CuCl(2) as a tracer.	cupric chloride	247-254	ATPase, Cu++ transporting, beta polypeptide	Mus musculus	114-119