PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31157476-5 2019 In addition, Western blot analysis indicated that cynaroside protected ARPE-19 cells from apoptosis through downregulation of caspase-3 protein activation which was controlled by the upstream proteins Bcl-2 and Bax. luteolin-7-glucoside 50-60 BCL2 apoptosis regulator Homo sapiens 201-206 29874795-4 2018 The study demonstrated that luteoloside could inhibit proliferation remarkably; promote apoptosis and cytochrome C release; decrease the mitochondrial membrane potential and reactive oxygen species level; upregulate the expression of Fas, Bax, p53, phospho-p38, phospho-JNK, and cleaved PARP; downregulate the expression of Bcl-2 and phospho-mTOR; activate caspase-3 and caspase-8; change the nuclear morphology, and fragmentate DNA in Hela cells. luteolin-7-glucoside 28-39 BCL2 apoptosis regulator Homo sapiens 324-329