PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33984439-0	2021	Cynaroside prevents macrophage polarization into pro-inflammatory phenotype and alleviates cecal ligation and puncture-induced liver injury by targeting PKM2/HIF-1alpha axis.	luteolin-7-glucoside	0-10	pyruvate kinase, muscle	Mus musculus	153-157	
33984439-6	2021	We established that cynaroside reduced binding of PKM2 to hypoxia-inducible factor-1alpha (HIF-1alpha) by abolishing translocation of PKM2 to the nucleus and promoting PKM2 tetramer formation, as well as suppressing phosphorylation of PKM2 at Y105 in vivo and in vitro.	luteolin-7-glucoside	20-30	pyruvate kinase, muscle	Mus musculus	50-54	
33984439-6	2021	We established that cynaroside reduced binding of PKM2 to hypoxia-inducible factor-1alpha (HIF-1alpha) by abolishing translocation of PKM2 to the nucleus and promoting PKM2 tetramer formation, as well as suppressing phosphorylation of PKM2 at Y105 in vivo and in vitro.	luteolin-7-glucoside	20-30	pyruvate kinase, muscle	Mus musculus	134-138	
33984439-6	2021	We established that cynaroside reduced binding of PKM2 to hypoxia-inducible factor-1alpha (HIF-1alpha) by abolishing translocation of PKM2 to the nucleus and promoting PKM2 tetramer formation, as well as suppressing phosphorylation of PKM2 at Y105 in vivo and in vitro.	luteolin-7-glucoside	20-30	pyruvate kinase, muscle	Mus musculus	134-138	
33984439-6	2021	We established that cynaroside reduced binding of PKM2 to hypoxia-inducible factor-1alpha (HIF-1alpha) by abolishing translocation of PKM2 to the nucleus and promoting PKM2 tetramer formation, as well as suppressing phosphorylation of PKM2 at Y105 in vivo and in vitro.	luteolin-7-glucoside	20-30	pyruvate kinase, muscle	Mus musculus	134-138