PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10535385-6	1999	Experiments performed on cytochalasin D-treated cells using Mn2+ as an indicator of Ca2+ influx quenched fura-2 fluorescence signals following vasopressin administration.	Fura-2	105-111	arginine vasopressin	Rattus norvegicus	143-154	
17125880-6	2007	Also, the temporal pattern of vasopressin-elicited intracellular calcium oscillations studied on fura2-loaded cells was altered, with the duration of each Ca2+ peak being longer.	Fura-2	97-102	arginine vasopressin	Rattus norvegicus	30-41	
8914016-2	1996	The AVP-induced cellular signal transduction, including inositol 1,4,5-trisphosphate (IP3) production, fura-2 intracellular calcium measurements and cellular alkalinization, was significantly greater in cells of SHR than those of WKY.	Fura-2	103-109	arginine vasopressin	Rattus norvegicus	4-7	
9808762-2	1998	Immunoblot analysis revealed that A7r5 vascular smooth muscle cells expressed conventional (alpha), novel (delta and epsilon), and atypical (iota/lambda and mu) isoforms of protein kinase C. Stimulation of fura-2-loaded cells with 20 nM vasopressin induced a rapid transient increase in the intracellular concentration of calcium that was followed by a slowly declining component which was above baseline throughout the period of observation.	Fura-2	206-212	arginine vasopressin	Rattus norvegicus	237-248	
8913359-3	1996	By videomicroscopically examining Fura-2-loaded cells, we demonstrate that vasopressin induces a dose-dependent and receptor-mediated calcium influx fully inhibited by either 1 microM nifedipine or a pertussis toxin pretreatment and potentiated by 1 microM BAY K 8644.	Fura-2	34-40	arginine vasopressin	Rattus norvegicus	75-86	
9065736-2	1997	Using fura-2-loaded cells, we observed that the release induced by AVP occurred concurrently with calcium (Ca2+) mobilization from internal stores and entry of external Ca2+, whereas AlF4(-)-dependent arachidonate release was much slower and was not accompanied by intracellular Ca2+ mobilization.	Fura-2	6-12	arginine vasopressin	Rattus norvegicus	67-70	
7666368-2	1995	Arg8-vasopressin (AVP)-regulated Ca2+ transport were investigated in fura-2-loaded A7r5 cells using both single cell and population measurements.	Fura-2	69-75	arginine vasopressin	Rattus norvegicus	0-16	
8780286-2	1996	Using digital imaging microscopy with the Ca2+ indicator fura-2, the effects of halothane on the intracellular [Ca2+] dynamics induced by arginine vasopressin (AVP) in the perinuclear region and cytosol in single cultured smooth muscle cells of rat aorta were studied.	Fura-2	57-63	arginine vasopressin	Rattus norvegicus	147-158	
8780286-2	1996	Using digital imaging microscopy with the Ca2+ indicator fura-2, the effects of halothane on the intracellular [Ca2+] dynamics induced by arginine vasopressin (AVP) in the perinuclear region and cytosol in single cultured smooth muscle cells of rat aorta were studied.	Fura-2	57-63	arginine vasopressin	Rattus norvegicus	160-163	
8756565-3	1996	Video microscopy experiments performed on fura-2-loaded adrenal medullary or adrenal glomerulosa cell primary cultures showed that vasopressin dose dependently mobilized intracellular calcium, suggesting that functional vasopressin receptors are expressed in these tissues.	Fura-2	42-48	arginine vasopressin	Rattus norvegicus	131-142	
8756565-3	1996	Video microscopy experiments performed on fura-2-loaded adrenal medullary or adrenal glomerulosa cell primary cultures showed that vasopressin dose dependently mobilized intracellular calcium, suggesting that functional vasopressin receptors are expressed in these tissues.	Fura-2	42-48	arginine vasopressin	Rattus norvegicus	220-231	
8611034-2	1996	In fura-2-loaded cells, AVP induced a rapid (0.5-2 min) transient increase in [Ca2+]i that was followed by a smaller sustained increase in [Ca2+]i.	Fura-2	3-9	arginine vasopressin	Rattus norvegicus	24-27	
8589290-6	1995	Fura-2 fluorescence ratio was not significantly changed with angiotensin II, Ap3A, or Ap4A but increased with vasopressin, ATP, Ap5A, and Ap6A by 0.08 +/- 0.02 (N = 13), 0.04 +/- 0.02 (N = 13), 0.03 +/- 0.01 (N = 14), and 0.03 +/- 0.01 (N = 10), respectively.	Fura-2	0-6	arginine vasopressin	Rattus norvegicus	110-121	
7666368-2	1995	Arg8-vasopressin (AVP)-regulated Ca2+ transport were investigated in fura-2-loaded A7r5 cells using both single cell and population measurements.	Fura-2	69-75	arginine vasopressin	Rattus norvegicus	18-21	
8382636-2	1993	The flux through ROCCs was followed by quenching of fura-2 fluorescence due to the influx of extracellular Mn2+ induced by vasopressin.	Fura-2	52-58	arginine vasopressin	Rattus norvegicus	123-134	
8293556-7	1994	By use of Mn2+ quenching of intracellular fura 2 to measure divalent cation entry, the maximal rate of vasopressin-stimulated Mn2+ entry was impaired in simvastatin-treated cells by 52%.	Fura-2	42-48	arginine vasopressin	Rattus norvegicus	103-114	
8387925-5	1993	Fluorescent ratio imaging with fura-2 revealed that addition of vasopressin to the cells results in an increase of [Ca2+]i which peaks within 20 s and does not return to resting levels during the 100 s observation period.	Fura-2	31-37	arginine vasopressin	Rattus norvegicus	64-75	
8068023-2	1994	Similarly, in cells microinjected with Fura-2 salt, vasopressin stimulated Mn2+ entry while 2,5-di-(t-butyl)hydroquinone or thapsigargin did not.	Fura-2	39-45	arginine vasopressin	Rattus norvegicus	52-63	
1329268-2	1992	Both AII and AVP specifically induce a transient increases in cytosolic free calcium independent of extracellular calcium or calcium channels activated by high potassium depolarization in VSM cells loaded with Fura-2.	Fura-2	210-216	arginine vasopressin	Rattus norvegicus	13-16	
1393572-4	1992	Using Fura-2 loaded cells and dynamic ratio imaging, we have determined that arginine vasopressin (AVP) or V1- but not V2-receptor agonists, mobilise pituicyte intracellular Ca2+ ([Ca2+]i) in the absence of extracellular Ca2+.	Fura-2	6-12	arginine vasopressin	Rattus norvegicus	77-109	
1939188-0	1991	Oscillations of intracellular calcium induced by vasopressin in individual fura-2-loaded mesangial cells.	Fura-2	75-81	arginine vasopressin	Rattus norvegicus	49-60	
2548389-11	1989	The time course of the initial hyperpolarization was shown to be similar to the calcium transient observed in fura-2-loaded A10 cell suspensions after the application of AVP.	Fura-2	110-116	arginine vasopressin	Rattus norvegicus	170-173	
2170382-3	1990	In the presence of extracellular Mn2+, the Ca2(+)-mobilizing hormone vasopressin produced a severalfold stimulation of the basal rate of fura-2 fluorescence quenching as a result of Mn2+ influx; this effect was blocked by the presence of Ni2+ in the incubation medium.	Fura-2	137-143	arginine vasopressin	Rattus norvegicus	69-80	
3014901-6	1986	With fura-2 as the intracellular Ca2+ indicator, [Ca2+]f increased from 74 +/- 7 to a peak of 578 +/- 39 nM (n = 17) with 100 nM AVP.	Fura-2	5-11	arginine vasopressin	Rattus norvegicus	129-132	
2731227-2	1989	When stimulated with the agonists, angiotensin II and arginine vasopressin, cells incubated with low concentrations of fura-2 or indo-1 (less than 1 microM) produced Ca2+ transients characterized by a small increase followed by a dramatic decrease in fluorescence below the original baseline.	Fura-2	119-125	arginine vasopressin	Rattus norvegicus	63-74