PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15326217-4	2004	We measured cytosolic Ca(2+) concentration ([Ca(2+)](i)) in fura-2-loaded VSM of anterior mesenteric artery of Squalus acanthias and show that the ET(B)R agonists IRL 1620 and sarafotoxin S6c (SRX) increase [Ca(2+)](i) in VSM to the same extent as ET-1 and ET(B)R appears to be the only ETR subtype in sharks.	Fura-2	60-66	endothelin 1	Homo sapiens	248-252	
20725140-4	2010	Using intact and isolated human hVECs and the Fura-2 calcium (Ca2+) measurement technique, we showed that ET-1 induced a dose-dependent increase of total intracellular free Ca2+, with an EC50 of 1.3 x 10-10 mol/L.	Fura-2	46-52	endothelin 1	Homo sapiens	106-110	
18289524-4	2008	Measurement of the Ca2+ signal in fura-2-loaded cells allowed to characterize endothelin-1-evoked Ca2+ entry, which was resistant to dihydropyridine, and was blocked by 2-aminoethoxydiphenylborate (2-APB) and micromolar concentration of Gd3+.	Fura-2	34-40	endothelin 1	Homo sapiens	78-90	
14638730-9	2003	Intracellular Ca(2+) ([Ca(2+)](i)) mobilization mediated by ET-1 was measured using the Fura-2 AM fluorescent probe technique as an index of ET receptor function.	Fura-2	88-94	endothelin 1	Homo sapiens	60-64	
14966371-3	2004	Among a variety of Ca(2+)-related agents tested, EGTA and thapsigargin were found to suppress both the glucose uptake and intracellular Ca(2+) mobilization induced by ET-1, as determined by Fura-2 analysis.	Fura-2	190-196	endothelin 1	Homo sapiens	167-171	
12147606-6	2002	ET-1-induced intracellular calcium ([Ca2+]i) in hONAs was measured by fura-2 imaging.	Fura-2	70-76	endothelin 1	Homo sapiens	0-4	
9816080-5	1995	In fura-2-loaded ovarian carcinoma cells, ET-1 induced dose-dependent increases in cytoplasmic Ca2+ concentration.	Fura-2	3-9	endothelin 1	Homo sapiens	42-46	
9105731-1	1997	Ca2+ transients evoked by endothelin-1 (ET-1) were measured in single cells of an immortalized human tracheal epithelial cell line using Fura-2.	Fura-2	137-143	endothelin 1	Homo sapiens	40-44	
10532691-4	1999	Furthermore, ET-1 stimulated protein synthesis (maximum 73 +/- 32% increase in [3H]leucine incorporation by 10(-7) M (P < 0.05)), as well as triggering intracellular calcium transients in human cSMC, as visualised under fura-2 fluorescence microscopy.	Fura-2	223-229	endothelin 1	Homo sapiens	13-17	
7705470-1	1994	We examined the mechanism of endothelin-1-induced contraction in the porcine coronary artery by assessing the changes in myosin light chain phosphorylation and cytosolic Ca2+ concentration ([Ca2+]i) determined by fura-2 and front-surface fluorometry.	Fura-2	213-219	endothelin 1	Homo sapiens	29-41	
8001384-5	1995	MEASUREMENTS AND MAIN RESULTS: Endothelin-1 increased the intracellular calcium concentration in fura-2 loaded human monocytes to a mean value of 37 +/- 4 nmol.	Fura-2	97-103	endothelin 1	Homo sapiens	31-43	
8124662-1	1994	Angiotensin II (Ang II), bradykinin (BK), and endothelin-1 (ET-1) evoked alterations in cytosolic free calcium, [Ca2+]i, levels were determined using fura-2 fluorescence methodology in a human lung adenocarcinoma cell line (A549), a non-neoplastic lung cell line and a small cell lung carcinoma cell (SCLC) line.	Fura-2	150-156	endothelin 1	Homo sapiens	46-58	
8124662-1	1994	Angiotensin II (Ang II), bradykinin (BK), and endothelin-1 (ET-1) evoked alterations in cytosolic free calcium, [Ca2+]i, levels were determined using fura-2 fluorescence methodology in a human lung adenocarcinoma cell line (A549), a non-neoplastic lung cell line and a small cell lung carcinoma cell (SCLC) line.	Fura-2	150-156	endothelin 1	Homo sapiens	60-64	
1323639-4	1992	ET-1 dose-dependently (1-100 nmol/l) induced rapid and transient increases in [Ca2+]i in fura-2-labelled cells.	Fura-2	89-95	endothelin 1	Homo sapiens	0-4	
2172374-2	1990	Endothelin-1 was found to increase the intracellular Ca2+ level, either in the presence or absence of extracellular Ca2+, in endothelial cells pretreated with antiserum by the fura-2 fluorescence technique.	Fura-2	176-182	endothelin 1	Homo sapiens	0-12	
2022753-6	1991	ET-1 dose-dependently induced increases in cytosolic free Ca2+ concentration in fura-2-loaded tumor cells, whose effect was completely abolished by chelating extracellular Ca2+ or by Ca(2+)-channel blocker.	Fura-2	80-86	endothelin 1	Homo sapiens	0-4