PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24157978-1 2013 We examined the endothelin-1 (ET-1)-induced increase in the intracellular free Ca(2+) concentration ([Ca(2+)]i) in fura-2-loaded rat pulmonary small arteries. Fura-2 115-121 endothelin 1 Rattus norvegicus 16-28 24157978-1 2013 We examined the endothelin-1 (ET-1)-induced increase in the intracellular free Ca(2+) concentration ([Ca(2+)]i) in fura-2-loaded rat pulmonary small arteries. Fura-2 115-121 endothelin 1 Rattus norvegicus 30-34 15309721-8 2004 Fura-2/AM loaded HSC was suspended in no Ca2+ buffer containing 1 mol/L EGTA, 5 min later, 10(-8) mol/L of ET-1 was added, [Ca2+]i inward HSCs rose from resting state to peak 399+/-123 mol/L, then began to come down by the time of 20 min. Fura-2 0-6 endothelin 1 Rattus norvegicus 107-111 21873674-7 2011 ET-1-induced ONHA fura-2 ratio increases were significantly greater in TSL ONHAs (by 20% at 10-7 M and by 48% at 10-9 M) compared with WT ONHAs. Fura-2 18-24 endothelin 1 Rattus norvegicus 0-4 21873674-8 2011 ET-1-induced fura-2 ratio increases were blocked after pretreatment with BQ-610 (ETA antagonist) in WT and TSL ONHAs, but not by BQ-788 (ETB antagonist) in WT ONHAs. Fura-2 13-19 endothelin 1 Rattus norvegicus 0-4 10919286-6 2000 Moreover, binding sites for endothelin-1 were increased, and the calcium response to the contractile agonist, determined in single fura-2-loaded cells, was enhanced. Fura-2 131-137 endothelin 1 Rattus norvegicus 28-40 1380304-1 1992 In individual fura-2 loaded cells of rat pancreatic acini endothelin-1 (ET-1) (10-50 nM) induced sustained oscillations in [Ca2+]i. Fura-2 14-20 endothelin 1 Rattus norvegicus 58-70 10629863-1 1999 To clarify Ca2+ entry channels involved in the endothelin-1 (ET-1)-induced increase in the intracellular concentration ([Ca2+]i), we performed whole-cell recordings of patch-clamp techniques and monitoring of [Ca2+]i with Ca2+ indicators fura-2 and fluo-3 in A7r5 cells (a cell line derived from rat thoracic aortic smooth muscle cells). Fura-2 238-244 endothelin 1 Rattus norvegicus 47-59 10629863-1 1999 To clarify Ca2+ entry channels involved in the endothelin-1 (ET-1)-induced increase in the intracellular concentration ([Ca2+]i), we performed whole-cell recordings of patch-clamp techniques and monitoring of [Ca2+]i with Ca2+ indicators fura-2 and fluo-3 in A7r5 cells (a cell line derived from rat thoracic aortic smooth muscle cells). Fura-2 238-244 endothelin 1 Rattus norvegicus 61-65 1380304-1 1992 In individual fura-2 loaded cells of rat pancreatic acini endothelin-1 (ET-1) (10-50 nM) induced sustained oscillations in [Ca2+]i. Fura-2 14-20 endothelin 1 Rattus norvegicus 72-76 1650480-1 1991 Endothelin 1 causes a strong Ca2+ signal in C6 rat glioma cells as measured by fura-2 fluorescence. Fura-2 79-85 endothelin 1 Rattus norvegicus 0-12 1725305-1 1991 The present study was undertaken to examine the interaction between endothelin-1 (ET-1)-induced Ca2+ and Na+ kinetics in cultured rat vascular smooth muscle cells (VSMCs) by measuring cytosolic free Ca2+ ([Ca2+]i) and intracellular Na+ ([Na+]i) using intracellular fluorescent dyes (fura-2 and SBFI, respectively). Fura-2 283-289 endothelin 1 Rattus norvegicus 68-80 1725355-6 1991 ET-1 caused a prompt rise in the fura-2-associated fluorescence intensity in the individual A-10 cell and it fell to a lower plateau level that was still higher than the baseline value. Fura-2 33-39 endothelin 1 Rattus norvegicus 0-4 1725410-5 1991 By fura-2 fluorescence method, transient increase and oscillation of intracellular Ca2+ level were observed in the cultured myofibroblasts following the application of ET-1 or endothelin-3 (ET-3). Fura-2 3-9 endothelin 1 Rattus norvegicus 168-172 1725305-1 1991 The present study was undertaken to examine the interaction between endothelin-1 (ET-1)-induced Ca2+ and Na+ kinetics in cultured rat vascular smooth muscle cells (VSMCs) by measuring cytosolic free Ca2+ ([Ca2+]i) and intracellular Na+ ([Na+]i) using intracellular fluorescent dyes (fura-2 and SBFI, respectively). Fura-2 283-289 endothelin 1 Rattus norvegicus 82-86 2473295-4 1989 ET-1 dose-dependently induced increases in [Ca2+]i of both cells loaded with the fluorescent Ca2+ indicator fura-2. Fura-2 108-114 endothelin 1 Rattus norvegicus 0-4 2260994-5 1990 Pretreatment with the phospholipase A2 inhibitor dexamethasone potently inhibited both ET-1 and PAF-induced elevation of cytosolic free Ca2+ concentrations [( Ca2+]i) in fura-2-loaded VSMC. Fura-2 170-176 endothelin 1 Rattus norvegicus 87-91 2473325-6 1989 ET-1 and EC-CM induced a dose-dependent increase in steady-state [Ca2+]i in Fura-2-loaded rat VSM cells. Fura-2 76-82 endothelin 1 Rattus norvegicus 0-4