PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28535922-3	2017	The potencies of PFASs to inhibit SRD5A1 are PFOS > PFOA > PFHxS = PFBS, with IC50 values of PFOS and PFOA of 1.92 +- 0.07 and 14.24 +- 0.07 muM and no effects for PFHxS and PFBS at 100 muM, respectively.	3-O-(N-(p-fluorobenzenesulfonyl)carbamoyl)oleanolic acid	55-59	steroid 5 alpha-reductase 1	Rattus norvegicus	34-40	
28535922-3	2017	The potencies of PFASs to inhibit SRD5A1 are PFOS > PFOA > PFHxS = PFBS, with IC50 values of PFOS and PFOA of 1.92 +- 0.07 and 14.24 +- 0.07 muM and no effects for PFHxS and PFBS at 100 muM, respectively.	3-O-(N-(p-fluorobenzenesulfonyl)carbamoyl)oleanolic acid	108-112	steroid 5 alpha-reductase 1	Rattus norvegicus	34-40	
28535922-5	2017	PFOS and PFOA competitively inhibited rat SRD5A1.	3-O-(N-(p-fluorobenzenesulfonyl)carbamoyl)oleanolic acid	9-13	steroid 5 alpha-reductase 1	Rattus norvegicus	42-48	
28535922-6	2017	In conclusion, PFOS and PFOA are potent inhibitors of rat SRD5A1, thereby controlling the biosynthesis of neurosteroids.	3-O-(N-(p-fluorobenzenesulfonyl)carbamoyl)oleanolic acid	24-28	steroid 5 alpha-reductase 1	Rattus norvegicus	58-64