PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26151430-4 2015 Time-dependent quenching of flavin fluorescence was used to monitor halotyrosine association to IYD. 4,6-dinitro-o-cresol 28-34 iodotyrosine deiodinase Homo sapiens 96-99 30052294-3 2019 The co-crystal of F-Tyr and a T239A variant of human IYD have now been characterized to provide a structural basis for control of its flavin reactivity. 4,6-dinitro-o-cresol 134-140 iodotyrosine deiodinase Homo sapiens 53-56 30052294-6 2019 Even substitution of Thr with Ser decreases the midpoint potential of human IYD between its oxidized and semiquinone forms of flavin by almost 80 mV. 4,6-dinitro-o-cresol 126-132 iodotyrosine deiodinase Homo sapiens 76-79 19436071-6 2009 Substrate coordination to IYD induces formation of an additional helix and coil that act as an active site lid to shield the resulting substrate.flavin complex from solvent. 4,6-dinitro-o-cresol 145-151 iodotyrosine deiodinase Homo sapiens 26-29 28774660-1 2017 Iodotyrosine deiodinase (IYD) is unusual for its reliance on flavin to promote reductive dehalogenation under aerobic conditions. 4,6-dinitro-o-cresol 61-67 iodotyrosine deiodinase Homo sapiens 0-23 28774660-1 2017 Iodotyrosine deiodinase (IYD) is unusual for its reliance on flavin to promote reductive dehalogenation under aerobic conditions. 4,6-dinitro-o-cresol 61-67 iodotyrosine deiodinase Homo sapiens 25-28