PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29487133-5	2018	We found that the most potent BLVRB inhibitors contain a tricyclic hydrocarbon core structure similar to the isoalloxazine ring of flavin mononucleotide and that both xanthene- and acridine-based compounds inhibit BLVRB"s flavin and dichlorophenolindophenol (DCPIP) reductase functions.	4,6-dinitro-o-cresol	131-137	biliverdin reductase B	Homo sapiens	30-35	
27207795-4	2016	BLVRB(S111L) encompassed within the substrate/cofactor [alpha/beta dinucleotide NAD(P)H] binding fold is a functionally defective redox coupler using flavin and biliverdin (BV) IXbeta tetrapyrrole(s) and results in exaggerated reactive oxygen species accumulation as a putative metabolic signal leading to differential hematopoietic lineage commitment and enhanced thrombopoiesis.	4,6-dinitro-o-cresol	150-156	biliverdin reductase B	Homo sapiens	0-5	
10858451-8	2000	The flavin reductase activity of biliverdin-IXbeta reductase is potently inhibited by mesobiliverdin-XIIIalpha and protohemin, which is consistent with the hypothesis that the tetrapyrrole and flavin substrate bind at a common site.	4,6-dinitro-o-cresol	4-10	biliverdin reductase B	Homo sapiens	33-60	
34095235-1	2021	The biliverdin reductase B (BLVRB) class of enzymes catalyze the NADPH-dependent reduction of multiple flavin substrates and are emerging as critical players in cellular redox regulation.	4,6-dinitro-o-cresol	103-109	biliverdin reductase B	Homo sapiens	4-26	
34095235-1	2021	The biliverdin reductase B (BLVRB) class of enzymes catalyze the NADPH-dependent reduction of multiple flavin substrates and are emerging as critical players in cellular redox regulation.	4,6-dinitro-o-cresol	103-109	biliverdin reductase B	Homo sapiens	28-33	
7400118-0	1980	Reduction of methemoglobin through flavin at the physiological concentration by NADPH-flavin reductase of human erythrocytes.	4,6-dinitro-o-cresol	35-41	biliverdin reductase B	Homo sapiens	80-102	
7400118-5	1980	These results apparently suggest that the NADPH-flavin reductase system is able to reduce methemoglobin in erythrocytes at a moderate speed with about 1 microM flavin, and the reduction was estimated to vary from less than 1% to about 20% of that by the NADH-cytochrome b5 reductase system with 1 microM cytochrome b5, depending on the uptake of flavin by human erythrocytes.	4,6-dinitro-o-cresol	160-166	biliverdin reductase B	Homo sapiens	42-64