PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16450155-0	2006	Hydrochlorothiazide efficacy and polymorphisms in ACE, ADD1 and GNB3 in healthy, male volunteers.	Hydrochlorothiazide	0-19	adducin 1	Homo sapiens	55-59	
16266470-0	2005	[Association of polymorphism in alpha-adducin gene with antihypertensive effect of Hydrochlorothiazide].	Hydrochlorothiazide	83-102	adducin 1	Homo sapiens	32-45	
16266470-1	2005	OBJECTIVE: To explore the association between G614T single nuclear polymorphism (SNP) of the alpha-adducin gene and the antihypertensive effect of hydrochlorothiazide (HCTZ) in essential hypertensive (EH) patients.	Hydrochlorothiazide	147-166	adducin 1	Homo sapiens	93-106	
16266470-1	2005	OBJECTIVE: To explore the association between G614T single nuclear polymorphism (SNP) of the alpha-adducin gene and the antihypertensive effect of hydrochlorothiazide (HCTZ) in essential hypertensive (EH) patients.	Hydrochlorothiazide	168-172	adducin 1	Homo sapiens	93-106	
16266470-5	2005	RESULTS: After 6 weeks of HCTZ treatment, the decreases in DBP and MAP of patients carrying 614T allele of alpha-adducin were significantly greater than that of those carrying GG homozygotes (P < 0.05).	Hydrochlorothiazide	26-30	adducin 1	Homo sapiens	107-120	
16266470-9	2005	CONCLUSION: The present study suggests that the alpha-adducin G614T polymorphism is associated with the antihypertensive effect of HCTZ, which is more effective in patients with TT genotype.	Hydrochlorothiazide	131-135	adducin 1	Homo sapiens	48-61	
23863317-0	2013	Effects of ACE and ADD1 gene polymorphisms on blood pressure response to hydrochlorothiazide: a meta-analysis.	Hydrochlorothiazide	73-92	adducin 1	Homo sapiens	19-23	
23863317-3	2013	A meta-analysis of published data was conducted to evaluate the pharmacogenetic associations of ACE I/D and ADD1 Gly460Trp polymorphisms with blood pressure changes during HCTZ therapy.	Hydrochlorothiazide	172-176	adducin 1	Homo sapiens	108-112	
23863317-8	2013	This study is the first meta-analysis to evaluate the influences of ACE and ADD1 polymorphisms on blood pressure responses to HCTZ to combine the inconsistent results of previous studies.	Hydrochlorothiazide	126-130	adducin 1	Homo sapiens	76-80	
12623934-7	2003	Alpha-adducin and ACE I/D polymorphism may be useful to predict the interindividual degree of response to hydrochlorothiazide; the analysis of the combination of the 2 genotypes increases the accuracy of the prediction of response to the drug.	Hydrochlorothiazide	106-125	adducin 1	Homo sapiens	0-13