PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14708625-3 2003 The induction of interferon regulatory factor-1 protein and the up-regulation of interferon regulatory factor-1 mRNA levels was inhibited when cells were pretreated with the iron chelators 2-2-dipyridyl or deferoxamine. Deferoxamine 206-218 interferon regulatory factor 1 Homo sapiens 17-47 14708625-3 2003 The induction of interferon regulatory factor-1 protein and the up-regulation of interferon regulatory factor-1 mRNA levels was inhibited when cells were pretreated with the iron chelators 2-2-dipyridyl or deferoxamine. Deferoxamine 206-218 interferon regulatory factor 1 Homo sapiens 81-111 12633744-7 2003 Furthermore, treatment of HAEC with 0.5 mM DFO or NC completely inhibited TNFalpha-induced activation of the transcription factor, specificity protein-1 (SP-1), but only partially inhibited or did not affect activation of other transcription factors known to regulate adhesion molecule expression, i.e., nuclear factor kappaB (NFkappaB), activator protein-1 (AP-1), and interferon regulatory factor-1 (IRF-1). Deferoxamine 43-46 interferon regulatory factor 1 Homo sapiens 402-407 12633744-7 2003 Furthermore, treatment of HAEC with 0.5 mM DFO or NC completely inhibited TNFalpha-induced activation of the transcription factor, specificity protein-1 (SP-1), but only partially inhibited or did not affect activation of other transcription factors known to regulate adhesion molecule expression, i.e., nuclear factor kappaB (NFkappaB), activator protein-1 (AP-1), and interferon regulatory factor-1 (IRF-1). Deferoxamine 43-46 interferon regulatory factor 1 Homo sapiens 370-400