PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 4074790-2 1985 The increase in the intracellular concentrations of isocitrate and alpha-ketoglutarate with a simultaneous decrease of malate in the liver of vitamin-deficient rats points to the inhibition of alpha-ketoglutarate dehydrogenase responsible for the anomalous metabolism under conditions of thiamine deficiency. isocitric acid 52-62 oxoglutarate dehydrogenase Rattus norvegicus 193-226