PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9343833-1 1997 We investigated the effects of type of dietary fat and phenobarbital on gamma-glutamyl transpeptidase-positive foci development. Phenobarbital 55-68 gamma-glutamyltransferase 1 Rattus norvegicus 72-101 16777703-7 2006 Interestingly, pretreatment with PB prior to itraconazole reduced the ALT and gamma-GT activities and the liver weight of rats. Phenobarbital 33-35 gamma-glutamyltransferase 1 Rattus norvegicus 78-86 20585144-7 2010 However, increased liver alkaline phosphatase or gamma glutamyltransferase activity in dogs treated with phenobarbital or corticosteroids suggests that direct or indirect induction of select hepatobiliary injury markers can occur both in the absence of liver injury and independently of induction of DME activity. Phenobarbital 105-118 gamma-glutamyltransferase 1 Rattus norvegicus 49-74 10670821-6 2000 Potentiation of thioacetamide hepatotoxicity by phenobarbital pretreatment was demonstrated at morphological level, and by significant increases in the activities of serum aspartate aminotransferase and gamma-glutamyl transferase, and in the levels of total bilirubin. Phenobarbital 48-61 gamma-glutamyltransferase 1 Rattus norvegicus 203-229 9343833-8 1997 However, in the presence of phenobarbital, 15% corn oil significantly enhanced gamma-glutamyl transpeptidase-positive foci development compared with 10% fish oil (p < 0.05). Phenobarbital 28-41 gamma-glutamyltransferase 1 Rattus norvegicus 79-108 9343833-10 1997 In conclusion, there was an interaction between type of dietary fat and phenobarbital on gamma-glutamyl transpeptidase-positive foci development during hepatocarcinogenesis in rats. Phenobarbital 72-85 gamma-glutamyltransferase 1 Rattus norvegicus 89-118 8573185-9 1996 Using urinary excretion of the enzymes alkaline phosphatase and gamma-glutamyl transferase as an index of renal damage, we observed that pretreatment of rats with PB, which induced hepatic P450 (P450II2B1), protected against OTA nephrotoxicity, whereas cobalt-protoporphyrin IX pretreatment, which decreased P450 levels, exacerbated OTA nephrotoxicity. Phenobarbital 163-165 gamma-glutamyltransferase 1 Rattus norvegicus 64-90 1352315-0 1992 Quantitative image cytometry of hepatocytes expressing gamma-glutamyl transpeptidase and glutathione S-transferase in diethylnitrosamine-initiated rats treated with phenobarbital and/or phthalate esters. Phenobarbital 165-178 gamma-glutamyltransferase 1 Rattus norvegicus 55-84 8847705-2 1995 gamma-Glutamyltranspeptidase (GGT), a biochemical marker for identifying putative preneoplastic lesions in the liver, is highly expressed in phenobarbital (PB)-promoted altered hepatic foci but not in those promoted by peroxisome proliferators. Phenobarbital 141-154 gamma-glutamyltransferase 1 Rattus norvegicus 0-28 8847705-2 1995 gamma-Glutamyltranspeptidase (GGT), a biochemical marker for identifying putative preneoplastic lesions in the liver, is highly expressed in phenobarbital (PB)-promoted altered hepatic foci but not in those promoted by peroxisome proliferators. Phenobarbital 141-154 gamma-glutamyltransferase 1 Rattus norvegicus 30-33 8847705-2 1995 gamma-Glutamyltranspeptidase (GGT), a biochemical marker for identifying putative preneoplastic lesions in the liver, is highly expressed in phenobarbital (PB)-promoted altered hepatic foci but not in those promoted by peroxisome proliferators. Phenobarbital 156-158 gamma-glutamyltransferase 1 Rattus norvegicus 0-28 8847705-2 1995 gamma-Glutamyltranspeptidase (GGT), a biochemical marker for identifying putative preneoplastic lesions in the liver, is highly expressed in phenobarbital (PB)-promoted altered hepatic foci but not in those promoted by peroxisome proliferators. Phenobarbital 156-158 gamma-glutamyltransferase 1 Rattus norvegicus 30-33 8847705-8 1995 Both doses of CIP significantly inhibited the induction of GGT activity at 48 and 72 hours, whereas PB enhanced GGT activity. Phenobarbital 100-102 gamma-glutamyltransferase 1 Rattus norvegicus 112-115 8847705-11 1995 The results of this experiment show that CIP and PB have different effects on GGT activity and LTC4 concentration. Phenobarbital 49-51 gamma-glutamyltransferase 1 Rattus norvegicus 78-81 8095861-8 1993 This was, in part, owing to enhanced GGT expression in AHF with PB administration. Phenobarbital 64-66 gamma-glutamyltransferase 1 Rattus norvegicus 37-40 1349513-5 1992 PB treatment resulted in a 89% increase in the number of persistent gamma-glutamyl transpeptidase (GTT) nodules per cm2 section, a 278% increase in the area of persistent GGT nodules per cm2 section, and a 116% increase in the average area per persistent nodule. Phenobarbital 0-2 gamma-glutamyltransferase 1 Rattus norvegicus 68-97 1949030-10 1991 Short-term treatment (5 days) with PB produced a 2-fold increase in the number and total area of GGT-positive nodules in the DEN/AAF group, but it had no significant effect on the number, size distribution, or total area of GGT-positive nodules in the AFB group. Phenobarbital 35-37 gamma-glutamyltransferase 1 Rattus norvegicus 97-100 1348223-8 1992 Phenobarbital treatment greatly enhanced bromobenzene-induced GGT and LDH release into the lavage fluid in a dose-dependent manner. Phenobarbital 0-13 gamma-glutamyltransferase 1 Rattus norvegicus 62-65 1949030-10 1991 Short-term treatment (5 days) with PB produced a 2-fold increase in the number and total area of GGT-positive nodules in the DEN/AAF group, but it had no significant effect on the number, size distribution, or total area of GGT-positive nodules in the AFB group. Phenobarbital 35-37 gamma-glutamyltransferase 1 Rattus norvegicus 224-227 2379175-3 1990 PB produced the following changes: (a) accelerated appearance of neoplastic nodules and hepatocellular carcinoma (from 28 weeks onwards); (b) phenotypic changes in altered foci such as a shift from clear to eosinophilic appearance, enhanced expression of gamma-glutamyltranspeptidase and other markers, and more distinct borders from surrounding liver; (c) an increase in foci number; and (d) accelerated foci enlargement. Phenobarbital 0-2 gamma-glutamyltransferase 1 Rattus norvegicus 255-283 1707352-9 1991 Subsequent feeding with a 0.05% PB diet for 64 weeks resulted in slightly increased development of GGT-positive foci but not GST-P positive lesions or hyperplastic nodules, suggesting a lack of tumor-initiating activity of the oxidative DNA damage associated with redox enzyme modulations with or without menadione. Phenobarbital 32-34 gamma-glutamyltransferase 1 Rattus norvegicus 99-102 1681808-9 1991 Phenobarbital, methylcholanthrene and dexamethasone were found to increase significantly gamma-glutamyltransferase while tyrosine aminotransferase activity was enhanced by dexamethasone. Phenobarbital 0-13 gamma-glutamyltransferase 1 Rattus norvegicus 89-114 1975953-4 1990 PB, in contrast, increased GGT activity in periportal hepatocytes. Phenobarbital 0-2 gamma-glutamyltransferase 1 Rattus norvegicus 27-30 2886233-0 1987 Differential time-course of induction of rat liver gamma-glutamyltransferase and drug-metabolizing enzymes in the endoplasmic reticulum, Golgi and plasma membranes after a single phenobarbital injection. Phenobarbital 179-192 gamma-glutamyltransferase 1 Rattus norvegicus 51-76 2563599-3 1989 Promotion by phenobarbital caused an increased expression of both of these genes in altered hepatic focal lesions, although this was somewhat more variable in the case of the GGT gene. Phenobarbital 13-26 gamma-glutamyltransferase 1 Rattus norvegicus 175-178 2823419-7 1987 In the DEN/PB and BZ/PB groups the parenchyma showed increases (even before PB treatment started) in G-6PD and in gamma-glutamyl transpeptidase (gamma-GT) and decreases in GSH. Phenobarbital 11-13 gamma-glutamyltransferase 1 Rattus norvegicus 114-143 2823419-7 1987 In the DEN/PB and BZ/PB groups the parenchyma showed increases (even before PB treatment started) in G-6PD and in gamma-glutamyl transpeptidase (gamma-GT) and decreases in GSH. Phenobarbital 21-23 gamma-glutamyltransferase 1 Rattus norvegicus 114-143 2823419-10 1987 Both initiators caused a high incidence of foci positive for G-6PD and for gamma-GT; nodules induced by DEN/PB were mainly positive for gamma-GT and showed an erratic response to the other parameters. Phenobarbital 108-110 gamma-glutamyltransferase 1 Rattus norvegicus 136-144 2576915-1 1989 The effect of low concentration of hepatic glutathione on the induction of GGT by phenobarbitone was investigated. Phenobarbital 82-96 gamma-glutamyltransferase 1 Rattus norvegicus 75-78 2576673-1 1989 The effect of hepatic glutathione concentration on the induction of gamma-glutamyltransferase (GGT) activity by phenobarbitone was investigated. Phenobarbital 112-126 gamma-glutamyltransferase 1 Rattus norvegicus 95-98 2576673-2 1989 A single dose of phenobarbitone 100 mg/kg weight was given to rats, and the concentration of hepatic glutathione and GGT activity were measured. Phenobarbital 17-31 gamma-glutamyltransferase 1 Rattus norvegicus 117-120 2886233-2 1987 This study was conducted to follow as a function of time the activity of gamma-glutamyltransferase in the various membranes of rat liver cells after a single dose of phenobarbital (PB) (75 mg kg-1 body weight). Phenobarbital 166-179 gamma-glutamyltransferase 1 Rattus norvegicus 73-98 2886233-2 1987 This study was conducted to follow as a function of time the activity of gamma-glutamyltransferase in the various membranes of rat liver cells after a single dose of phenobarbital (PB) (75 mg kg-1 body weight). Phenobarbital 181-183 gamma-glutamyltransferase 1 Rattus norvegicus 73-98 2886233-3 1987 Gamma-glutamyltransferase induction was maximal 24 h after PB treatment in both the rough endoplasmic reticulum and the plasma membranes. Phenobarbital 59-61 gamma-glutamyltransferase 1 Rattus norvegicus 0-25 2886233-10 1987 Five days of continuous PB treatment induced by appearance of new gamma-glutamyltransferase isoforms in plasma membranes. Phenobarbital 24-26 gamma-glutamyltransferase 1 Rattus norvegicus 66-91 2886233-11 1987 We demonstrate that after a single injection of PB, gamma-glutamyltransferase activity increases simultaneously with some drug-metabolizing enzymes, such as total cytochrome P-450 but not with others, such as UDP-glucuronosyltransferases. Phenobarbital 48-50 gamma-glutamyltransferase 1 Rattus norvegicus 52-77 2872903-0 1986 Effects of in utero administration of phenobarbital on gamma-glutamyl transpeptidase. Phenobarbital 38-51 gamma-glutamyltransferase 1 Rattus norvegicus 55-84 2885770-1 1987 The activity of gamma-glutamyltransferase localized in isolated brain synaptic membranes- and microvessels-enriched fractions was assayed after treatment of rats with either phenobarbital or ethanol. Phenobarbital 174-187 gamma-glutamyltransferase 1 Rattus norvegicus 16-41 2885770-2 1987 Phenobarbital increased the activity of gamma-glutamyltransferase in microvessels, without alteration of synaptic membranes activity. Phenobarbital 0-13 gamma-glutamyltransferase 1 Rattus norvegicus 40-65 3802399-3 1987 As compared with basal diet, a diet containing 0.05% of PB and 0.1% of OZ enhanced, in both models, the development of gamma-glutamyltransferase-positive lesions in early stages. Phenobarbital 56-58 gamma-glutamyltransferase 1 Rattus norvegicus 119-144 2875809-7 1986 Furthermore, PB caused a 3-fold increase in the number of foci expressing cytochrome P450-PB, gamma-GT or both. Phenobarbital 13-15 gamma-glutamyltransferase 1 Rattus norvegicus 94-102 3015147-6 1986 Phenobarbital caused a small but statistically insignificant increase in gamma-glutamyl transferase activity: density gradient centrifugation studies indicated that the increased activity was predominantly in the biliary canalicular elements. Phenobarbital 0-13 gamma-glutamyltransferase 1 Rattus norvegicus 73-99 2872903-1 1986 The present study was undertaken to determine the effects of the in utero administration of phenobarbital (Pb) on gamma glutamyl transpeptidase (gamma-GTP) in rats. Phenobarbital 92-105 gamma-glutamyltransferase 1 Rattus norvegicus 114-143 2872903-1 1986 The present study was undertaken to determine the effects of the in utero administration of phenobarbital (Pb) on gamma glutamyl transpeptidase (gamma-GTP) in rats. Phenobarbital 92-105 gamma-glutamyltransferase 1 Rattus norvegicus 145-154 2872903-1 1986 The present study was undertaken to determine the effects of the in utero administration of phenobarbital (Pb) on gamma glutamyl transpeptidase (gamma-GTP) in rats. Phenobarbital 107-109 gamma-glutamyltransferase 1 Rattus norvegicus 114-143 2872903-1 1986 The present study was undertaken to determine the effects of the in utero administration of phenobarbital (Pb) on gamma glutamyl transpeptidase (gamma-GTP) in rats. Phenobarbital 107-109 gamma-glutamyltransferase 1 Rattus norvegicus 145-154 2872903-8 1986 Brain gamma-GTP activity was found to be 0.00807 u in the Pb group and 0.00670 u in the control group. Phenobarbital 58-60 gamma-glutamyltransferase 1 Rattus norvegicus 6-15 2868808-2 1986 An increase in the incidence of gamma-glutamyltransferase (GGT)-positive hepatocytes was found in rats fed PB or DDT, while CPIB strikingly decreased the incidence. Phenobarbital 107-109 gamma-glutamyltransferase 1 Rattus norvegicus 32-57 2865001-0 1985 Promoting effects of phenobarbital and 3"-methyl-4-dimethylaminoazobenzene on the appearance of gamma-glutamyltranspeptidase positive foci in rat liver pretreated with varying doses of diethylnitrosamine. Phenobarbital 21-34 gamma-glutamyltransferase 1 Rattus norvegicus 96-124 2867834-4 1986 Withdrawing PB for 10 days resulted in a decrease in the number and volume of AHF, particularly those which stained positively for gamma-glutamyltranspeptidase (GGT). Phenobarbital 12-14 gamma-glutamyltransferase 1 Rattus norvegicus 131-159 3904978-6 1985 Hepatocytes from a male F344 donor rat that had received a 70% hepatectomy and 30 mg of diethylnitrosamine per kg and had been maintained on 0.05% PB for 12 mo formed GGT-positive colonies and hepatocellular carcinomas in both male and female recipients. Phenobarbital 147-149 gamma-glutamyltransferase 1 Rattus norvegicus 167-170 2865013-6 1985 gamma-GT was induced in periportal hepatocytes strongly by BHA and BHT and slightly by PB, and gamma-GT positive foci in periportal areas were not distinguishable from gamma-GT positive periportal hepatocytes. Phenobarbital 87-89 gamma-glutamyltransferase 1 Rattus norvegicus 0-8 2866268-6 1985 These levels were responsive to phenobarbital induction, although the induced levels in the GGT-positive cells were much lower than the induced levels in GGT-negative hepatocytes. Phenobarbital 32-45 gamma-glutamyltransferase 1 Rattus norvegicus 92-95 2866268-6 1985 These levels were responsive to phenobarbital induction, although the induced levels in the GGT-positive cells were much lower than the induced levels in GGT-negative hepatocytes. Phenobarbital 32-45 gamma-glutamyltransferase 1 Rattus norvegicus 154-157 2862989-3 1985 In contrast the livers of rats fed an equimolar concentration of phenobarbital displayed increases in cytosolic glutathione transferase activities and enhancement of gamma-glutamyl transpeptidase activity but no changes in glutathione peroxidase activities. Phenobarbital 65-78 gamma-glutamyltransferase 1 Rattus norvegicus 166-195 2863006-5 1985 Rats receiving PB had significantly increased numbers and volumes of eosinophilic and GGT-positive FHPL while the numbers and volumes of the common basophilic FHPL seen in controls were not affected by PB exposure. Phenobarbital 15-17 gamma-glutamyltransferase 1 Rattus norvegicus 86-89 2863006-7 1985 An uncommon GGT-positive FHPL found in control rats was detected in zone 1 of the hepatic acinus, a similar location of the GGT-positive eosinophilic FHPL seen in PB-exposed rats, while the common basophilic FHPL was observed in zones 1-3. Phenobarbital 163-165 gamma-glutamyltransferase 1 Rattus norvegicus 12-15 2863006-7 1985 An uncommon GGT-positive FHPL found in control rats was detected in zone 1 of the hepatic acinus, a similar location of the GGT-positive eosinophilic FHPL seen in PB-exposed rats, while the common basophilic FHPL was observed in zones 1-3. Phenobarbital 163-165 gamma-glutamyltransferase 1 Rattus norvegicus 124-127 2863006-8 1985 These findings suggest that PB does not promote the growth or development of the common naturally occurring basophilic FHPL but either promotes the uncommon GGT-positive FHPL or induces new FHPL de novo. Phenobarbital 28-30 gamma-glutamyltransferase 1 Rattus norvegicus 157-160 2863007-4 1985 The use of three markers in the present study confirmed the findings of our earlier study, which showed the maximal response of GGT+ AHF to PB administration following PH/DEN initiation and the stability of GGT+/AHF induced by the PH/DEN/PB regimen after the withdrawal of PB. Phenobarbital 140-142 gamma-glutamyltransferase 1 Rattus norvegicus 128-131 6142138-0 1984 Effect of coadministration of phenobarbital sodium on N-nitrosodiethylamine-induced gamma-glutamyltransferase-positive foci and hepatocellular carcinoma in rats. Phenobarbital 30-50 gamma-glutamyltransferase 1 Rattus norvegicus 84-109 6149821-0 1984 Effect of chronic phenobarbital administration on the gamma-glutamyl transpeptidase activity of hyperplastic liver lesions induced in rats by the Solt/Farber initiation: selection process of hepatocarcinogenesis. Phenobarbital 18-31 gamma-glutamyltransferase 1 Rattus norvegicus 54-83 6149821-1 1984 A chronic 8 to 11 week administration of the hepatic tumor promoter phenobarbital (0.05% in drinking water) to rats previously subjected to the initiation:selection process of Solt and Farber was found to further increase the gamma-glutamyl transpeptidase activity of individual hyperplastic liver nodules of 4.0-10.0 mm in diameter over comparably sized nodules from control livers. Phenobarbital 68-81 gamma-glutamyltransferase 1 Rattus norvegicus 226-255 6149821-3 1984 In addition, random tissue samples of non-nodular liver taken from the 11 week phenobarbital-treated rats exhibited a gamma-glutamyl transpeptidase mean specific activity which was approximately 3 times higher than that of control non-nodular liver samples. Phenobarbital 79-92 gamma-glutamyltransferase 1 Rattus norvegicus 118-147 6149821-4 1984 In contrast, there was a 1.5-fold increase in the mean % gamma-glutamyl transpeptidase-positive area (cm2), as determined histochemically, in cryostat sections made from non-nodular samples of the 11 week phenobarbital-treated rats when compared with that of control liver sections. Phenobarbital 205-218 gamma-glutamyltransferase 1 Rattus norvegicus 57-86 6149821-5 1984 Interruption of the chronic phenobarbital administration at 8 weeks followed by 3 weeks of control treatment resulted in a reversal of the gamma-glutamyl transpeptidase activity response shown by the hyperplastic liver nodules and non-nodular liver tissue samples. Phenobarbital 28-41 gamma-glutamyltransferase 1 Rattus norvegicus 139-168 6149821-6 1984 Thus, phenobarbital can quantitatively modulate gamma-glutamyl transpeptidase activity in carcinogen-induced hyperplastic liver lesions in the rat during the early stages of hepatocarcinogenesis. Phenobarbital 6-19 gamma-glutamyltransferase 1 Rattus norvegicus 48-77 2867096-10 1985 Furthermore, in the carcinogen-treated cultures, PB treatment caused a dose-dependent increase in the number of GGT positive cultures and in the percentage of GGT positive cells in each culture, and also caused a dose-dependent increase in the number of cultures with chromosomal abnormalities. Phenobarbital 49-51 gamma-glutamyltransferase 1 Rattus norvegicus 112-115 2867096-10 1985 Furthermore, in the carcinogen-treated cultures, PB treatment caused a dose-dependent increase in the number of GGT positive cultures and in the percentage of GGT positive cells in each culture, and also caused a dose-dependent increase in the number of cultures with chromosomal abnormalities. Phenobarbital 49-51 gamma-glutamyltransferase 1 Rattus norvegicus 159-162 6207184-2 1984 At 0.1 microgram/ml, TPA depressed the specific activities of lactate dehydrogenase and gamma-glutamyl transpeptidase, whereas 2 mM PB depressed gamma-glutamyl transpeptidase and alkaline phosphatase. Phenobarbital 132-134 gamma-glutamyltransferase 1 Rattus norvegicus 145-174 6207184-7 1984 The depression of gamma-glutamyl transpeptidase activity by PB is contradictory to that observed histochemically in hepatocytes in vivo, but such discrepancy may be related to the differences in cell type, growth conditions, or duration of exposure. Phenobarbital 60-62 gamma-glutamyltransferase 1 Rattus norvegicus 18-47 6498796-4 1984 BHA enhanced forestomach and urinary bladder carcinogenesis as did SA also for the urinary bladder, whereas PB enhanced the induction of gamma-glutamyl transpeptidase positive (gamma-GT+) foci in the liver and also the incidence of thyroid carcinoma and forestomach carcinoma. Phenobarbital 108-110 gamma-glutamyltransferase 1 Rattus norvegicus 137-166 6144610-9 1984 Administration of phenobarbital after N-2-fluorenylacetamide resulted in an elevation of liver and plasma gamma-glutamyltranspeptidase, but none of the benzodiazepines produced this effect and thus no biochemical evidence of a promoting effect on the liver was observed. Phenobarbital 18-31 gamma-glutamyltransferase 1 Rattus norvegicus 106-134 6142138-1 1984 The effect of concurrent administration of phenobarbital on the hepatocarcinogenicity of N-nitrosodiethylamine (diethylnitrosamine; DENA) in rats was investigated by determination of the incidence of gamma-glutamyltransferase (gamma-glutamyltranspeptidase) (GGT)-positive foci and liver tumors. Phenobarbital 43-56 gamma-glutamyltransferase 1 Rattus norvegicus 200-225 6150844-0 1984 [Histochemical appearance of gamma-glutamyltranspeptidase in the rat liver after transplacental exposure to diethylnitrosamine and postnatal administration of phenobarbital]. Phenobarbital 159-172 gamma-glutamyltransferase 1 Rattus norvegicus 29-57 6140087-2 1984 Phenobarbitone induced gamma-glutamyltranspeptidase activity in perilobular hepatocytes. Phenobarbital 0-14 gamma-glutamyltransferase 1 Rattus norvegicus 23-51 6199107-1 1983 The incidence of gamma-glutamyltranspeptidase (GGT)-positive foci induced by 0.3 mmol/kg diethylnitrosamine (DENA) followed by promotion with 500 ppm sodium phenobarbital in drinking water and was the same in Fischer 344, Sprague-Dawley and Wistar-Lewis rats. Phenobarbital 150-170 gamma-glutamyltransferase 1 Rattus norvegicus 47-50 6139159-0 1983 The effect of pre- and post-treatment with phenobarbital on the extent of gamma-glutamyl transpeptidase positive foci induced in rat liver by N-nitrosomorpholine. Phenobarbital 43-56 gamma-glutamyltransferase 1 Rattus norvegicus 74-103 6139159-3 1983 When given after the carcinogen treatment, phenobarbital enhanced the formation of gamma-GT-positive foci in liver compared with rats treated with NNM alone. Phenobarbital 43-56 gamma-glutamyltransferase 1 Rattus norvegicus 83-91 6115647-0 1981 Comparison of gamma-glutamyl transferase induction by phenobarbital in the rat, guinea pig and rabbit. Phenobarbital 54-67 gamma-glutamyltransferase 1 Rattus norvegicus 14-40 6135606-11 1983 Promotion by phenobarbital stimulated the growth and decreased the time required for the appearance of GGTase-positive foci and liver tumors. Phenobarbital 13-26 gamma-glutamyltransferase 1 Rattus norvegicus 103-109 6191977-6 1983 Of the miscellaneous compounds tested, phenobarbital, deoxycholic acid and ethynyl estradiol also induced gamma-glutamyl transpeptidase (gamma-GT) positive foci. Phenobarbital 39-52 gamma-glutamyltransferase 1 Rattus norvegicus 106-135 6191977-6 1983 Of the miscellaneous compounds tested, phenobarbital, deoxycholic acid and ethynyl estradiol also induced gamma-glutamyl transpeptidase (gamma-GT) positive foci. Phenobarbital 39-52 gamma-glutamyltransferase 1 Rattus norvegicus 137-145 6113606-6 1980 Phenobarbital administration to rats resulted in an enhancement of GGTP activity in the liver whether given orally or intraperitoneally. Phenobarbital 0-13 gamma-glutamyltransferase 1 Rattus norvegicus 67-71 6113606-7 1980 In addition, intestinal GGTP activity after oral phenobarbital was also significantly increased, although its activity after intraperitoneal administration was not enhanced. Phenobarbital 49-62 gamma-glutamyltransferase 1 Rattus norvegicus 24-28