PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11439219-0 2001 Phenobarbitone-induced liver response in wild type and in p53 deficient mice. Phenobarbital 0-14 transformation related protein 53, pseudogene Mus musculus 58-61 34695137-15 2021 Significant associations were found between p53 overexpression and histological grade (p = 0.034), triple negative (p = 0.0333) and luminal B (p<0.01) tumors. Phenobarbital 132-139 transformation related protein 53, pseudogene Mus musculus 44-47 33686070-4 2021 We found that perturbing Brca1/p53 in luminal progenitors induces aberrant alveolar differentiation pre-malignancy accompanied by pro-tumourigenic changes in the immune compartment. Phenobarbital 38-45 transformation related protein 53, pseudogene Mus musculus 31-34 33686070-6 2021 Based on our data we propose a model where Brca1/p53 LOF inadvertently promotes a differentiation program hardwired in luminal progenitors, highlighting the deterministic role of the cell-of-origin and offering a potential explanation for the tissue specificity of BRCA1 tumours. Phenobarbital 119-126 transformation related protein 53, pseudogene Mus musculus 49-52 9751125-6 1998 Phenobarbital inhibited both TGF-beta and bleomycin-induced apoptosis and the normal regulation of p53, bcl-2, and bax. Phenobarbital 0-13 transformation related protein 53, pseudogene Mus musculus 99-102 10449034-7 1999 Phenobarbital, a potent liver tumor promoter, inhibited apoptosis in c-myc hepatocytes but not in wild-type hepatocytes, decreased p53 and bax, and increased bcl-2 protein levels. Phenobarbital 0-13 transformation related protein 53, pseudogene Mus musculus 131-134 11311572-3 2001 We have investigated the effect of p53 on sodium phenobarbitone (PB)-induced liver proliferation and polyploidisation. Phenobarbital 42-63 transformation related protein 53, pseudogene Mus musculus 35-38 9683175-9 1998 A reduction in p53 protein, but not transcript levels, was observed in hepatocytes exposed to PB. Phenobarbital 94-96 transformation related protein 53, pseudogene Mus musculus 15-18 9683175-10 1998 Additionally, PB delayed and attenuated p53 protein induction during DNA damage, which suggests that changes in the p53 protein may be contributing to the attenuated G1 checkpoint response caused by PB. Phenobarbital 14-16 transformation related protein 53, pseudogene Mus musculus 40-43 9683175-10 1998 Additionally, PB delayed and attenuated p53 protein induction during DNA damage, which suggests that changes in the p53 protein may be contributing to the attenuated G1 checkpoint response caused by PB. Phenobarbital 14-16 transformation related protein 53, pseudogene Mus musculus 116-119 9683175-10 1998 Additionally, PB delayed and attenuated p53 protein induction during DNA damage, which suggests that changes in the p53 protein may be contributing to the attenuated G1 checkpoint response caused by PB. Phenobarbital 199-201 transformation related protein 53, pseudogene Mus musculus 116-119 9715508-1 1998 The tumorigenic potential of phenobarbital was examined in a 26-wk carcinogenesis bioassay using p53 heterozygous mice and wild-type controls. Phenobarbital 29-42 transformation related protein 53, pseudogene Mus musculus 97-100 9230198-5 1997 Dissociation of p53 proteins from degrading T antigens followed by a phenobarbital and c-myc-dependent, 15-fold induction of Bax protein, known to activate the apoptotic pathway downstream of p53, occurred in association with this phenomenon. Phenobarbital 69-82 transformation related protein 53, pseudogene Mus musculus 16-19 9230198-5 1997 Dissociation of p53 proteins from degrading T antigens followed by a phenobarbital and c-myc-dependent, 15-fold induction of Bax protein, known to activate the apoptotic pathway downstream of p53, occurred in association with this phenomenon. Phenobarbital 69-82 transformation related protein 53, pseudogene Mus musculus 192-195 8142011-0 1994 Screening for p53 mutations in C3H/He mouse liver tumors derived spontaneously or induced with diethylnitrosamine or phenobarbitone. Phenobarbital 117-131 transformation related protein 53, pseudogene Mus musculus 14-17