PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28785378-0	2017	Progression of Hepatic Adenoma to Carcinoma in Ogg1 Mutant Mice Induced by Phenobarbital.	Phenobarbital	75-88	8-oxoguanine DNA-glycosylase 1	Mus musculus	47-51	
28785378-4	2017	This was coordinated with PB-induced significant elevation of 8-OHdG formation in DNA and cell proliferation in adjacent liver of Ogg1-/- mice.	Phenobarbital	26-28	8-oxoguanine DNA-glycosylase 1	Mus musculus	130-134	
28785378-7	2017	Treatment of Ogg1-/- mice with PB resulted in significant elevation of cell proliferation in the liver.	Phenobarbital	31-33	8-oxoguanine DNA-glycosylase 1	Mus musculus	13-17	
28785378-8	2017	These results indicate that PB induced progression from HCA to HCC in Ogg1-/- mice, due to persistent accumulation of DNA oxidative base modifications and suppression of Nrf2-mediated oxidative stress response, resulting in significant elevation of cell proliferation.	Phenobarbital	28-30	8-oxoguanine DNA-glycosylase 1	Mus musculus	70-74	
28785378-1	2017	The carcinogenic potential of phenobarbital (PB) was assessed in a mouse line carrying a mutant Mmh allele of the Mmh/Ogg1 gene encoding the enzyme oxoguanine DNA glycosylase (Ogg1) responsible for the repair of 8-hydroxy-2"-deoxyguanosine (8-OHdG).	Phenobarbital	30-43	8-oxoguanine DNA-glycosylase 1	Mus musculus	176-180	
28785378-3	2017	Hepatocellular carcinomas (HCCs) were found in PB-treated Ogg1-/- mice, while Ogg1+/+ animals developed only hepatocellular adenomas (HCAs) at the same rate.	Phenobarbital	47-49	8-oxoguanine DNA-glycosylase 1	Mus musculus	58-62