PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18803253-0	2009	Docosahexaenoic acid downregulates phenobarbital-induced cytochrome P450 2B1 gene expression in rat primary hepatocytes via the c-Jun NH2-terminal kinase mitogen-activated protein kinase pathway.	Phenobarbital	35-48	mitogen-activated protein kinase 8	Rattus norvegicus	128-153	
18803253-8	2009	Both SP600125 (a JNK inhibitor) and SB203580 (a p38 MAPK inhibitor) inhibited CYP 2B1 protein and mRNA expression induced by phenobarbital.	Phenobarbital	125-138	mitogen-activated protein kinase 8	Rattus norvegicus	17-20	
18803253-10	2009	Our results suggest that inhibition of JNK activation by DHA is at least part of the mechanisms of DHA"s downregulation of CYP 2B1 expression induced by phenobarbital.	Phenobarbital	153-166	mitogen-activated protein kinase 8	Rattus norvegicus	39-42	
18803253-6	2009	c-Jun NH2-terminal kinase (JNK) JNK1/2 and ERK1/2 were activated by phenobarbital in a dose-dependent manner.	Phenobarbital	68-81	mitogen-activated protein kinase 8	Rattus norvegicus	0-25	
18803253-6	2009	c-Jun NH2-terminal kinase (JNK) JNK1/2 and ERK1/2 were activated by phenobarbital in a dose-dependent manner.	Phenobarbital	68-81	mitogen-activated protein kinase 8	Rattus norvegicus	27-30	
16154717-4	2006	We showed that PB induced an early, dose-dependent activation of ERK (extracellular signal-regulated kinase), JNK (c-Jun N-terminal kinase) and p38 MAPKs.	Phenobarbital	15-17	mitogen-activated protein kinase 8	Rattus norvegicus	110-113	
16154717-4	2006	We showed that PB induced an early, dose-dependent activation of ERK (extracellular signal-regulated kinase), JNK (c-Jun N-terminal kinase) and p38 MAPKs.	Phenobarbital	15-17	mitogen-activated protein kinase 8	Rattus norvegicus	115-138