PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15231049-2 2004 Using rat cDNA-expressed cytochrome P450 (CYP) enzymes, we found that phenacetin biotransformation was primarily mediated by CYP2C6 and CYP1A isoforms, while chlorzoxazone biotransformation was largely mediated by CYP2E1 and CYP1A1. Phenacetin 70-80 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 Rattus norvegicus 125-131 11911841-4 2002 On the other hand, phenacetin O-deethylation and 7-ethoxyresorufin O-deethylation were catalyzed both by CYP1A2 and by CYP2C6. Phenacetin 19-29 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 Rattus norvegicus 119-125