PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10597907-8 1999 Accelerated phenacetin and methoxyresorufin metabolism (CYP1A2) was also observed in the lung. Phenacetin 12-22 cytochrome P450, family 1, subfamily a, polypeptide 2 Mus musculus 56-62 10445756-0 1999 Role of CYP1A2 in the toxicity of long-term phenacetin feeding in mice. Phenacetin 44-54 cytochrome P450, family 1, subfamily a, polypeptide 2 Mus musculus 8-14 10445756-3 1999 CYP1A2 is known to metabolize phenacetin in vitro. Phenacetin 30-40 cytochrome P450, family 1, subfamily a, polypeptide 2 Mus musculus 0-6 10445756-7 1999 Consistent with the known role of CYP1A2 in phenacetin metabolism, plasma levels of phenacetin were higher and acetaminophen levels lower in the (-/-) mice fed phenacetin compared to phenacetin-fed (+/+) controls. Phenacetin 44-54 cytochrome P450, family 1, subfamily a, polypeptide 2 Mus musculus 34-40 10445756-14 1999 This provides evidence that metabolism of phenacetin by CYP1A2 alters toxicity in vivo, and suggests that alternate CYP1A2-independent metabolic pathways contribute to its toxicity. Phenacetin 42-52 cytochrome P450, family 1, subfamily a, polypeptide 2 Mus musculus 56-62