PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10548449-6	1999	In recombinant CYP from human B-lymphoblast cells, POD activities at a phenacetin concentration of 500 microM were detected for CYP2E1 and CYP3A4, as well as CYP1A2, CYP1A1, CYP2C19, CYP2C9 and CYP2A6.	Phenacetin	71-81	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	139-145	
20501911-3	2010	The kinetics of metabolite formation from phenacetin, tolbutamide, and alprazolam and midazolam, selected as substrates probes for CYP1A2, CYP2C9, and CYP3A4, respectively, were characterized in this in vitro system.	Phenacetin	42-52	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	151-157	
16857327-7	2006	Correlation analysis between the known CYP enzyme activities and the rates of the formation of 5-hydroxy- and 7-hydroxy-KR-33028 in the 16 human liver microsomes has showed significant correlations with CYP3A4-mediated midazolam 1"-hydroxylation and CYP1A2-mediated phenacetin O-deethylation, respectively.	Phenacetin	266-276	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	203-209	
25640685-2	2015	Phenacetin, dextromethorphan and testosterone, respectively, were used as CYP1A2, CYP2D6 and CYP3A4 substrates, and their metabolites were determined by validated HPLC methodologies.	Phenacetin	0-10	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	93-99	
10421611-5	1999	CYP1A1, CYP2C19, CYP2D6, CYP2E1, and CYP3A4 also showed POD activity at 500 microM phenacetin.	Phenacetin	83-93	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	37-43	
26614990-3	2015	Phenacetin O-deethylation, omeprazole hydroxylation and nifedipine oxidation were used as selective substrates for CYP1A2, CYP2C19 and CYP3A4 activities, respectively.	Phenacetin	0-10	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	135-141