PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31480528-6	2019	For this purpose, the O-deethylation reaction of phenacetin was used for monitoring CYP1A2 enzyme activity, coumarin 7-hydroxylation for CYP2A6 enzyme activity, 6-alpha-hydroxylation of paclitaxel for CYP2C8 enzyme activity, and dextromethorphan O-demethylation for CYP2D6 enzyme activity.	Phenacetin	49-59	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	137-143	
18779312-8	2008	Enzyme kinetics revealed that the CYP2A6 I208S/I300F/G301A/S369G mutant protein O-deethylated phenacetin with a K(m) of 10.3 muM and a k(cat) of 2.9 min(-1), which compare very favorably with those of CYP2A13 (K(m) of 10.7 muM and k(cat) of 3.8 min(-1)).	Phenacetin	94-104	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	34-40	
18779312-9	2008	A 2.15 A crystal structure of the mutant CYP2A6 I208S/I300F/G301A/S369G protein with phenacetin in the active site provided a structural rationale for the differences in phenacetin metabolism between CYP2A6 and CYP2A13.	Phenacetin	85-95	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	41-47	
18779312-9	2008	A 2.15 A crystal structure of the mutant CYP2A6 I208S/I300F/G301A/S369G protein with phenacetin in the active site provided a structural rationale for the differences in phenacetin metabolism between CYP2A6 and CYP2A13.	Phenacetin	85-95	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	200-206	
18779312-9	2008	A 2.15 A crystal structure of the mutant CYP2A6 I208S/I300F/G301A/S369G protein with phenacetin in the active site provided a structural rationale for the differences in phenacetin metabolism between CYP2A6 and CYP2A13.	Phenacetin	170-180	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	41-47	
18779312-9	2008	A 2.15 A crystal structure of the mutant CYP2A6 I208S/I300F/G301A/S369G protein with phenacetin in the active site provided a structural rationale for the differences in phenacetin metabolism between CYP2A6 and CYP2A13.	Phenacetin	170-180	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	200-206