PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27930695-0 2016 Coordinated Activation of VEGF/VEGFR-2 and PPARdelta Pathways by a Multi-Component Chinese Medicine DHI Accelerated Recovery from Peripheral Arterial Disease in Type 2 Diabetic Mice. dehydrosoyasaponin I 100-103 vascular endothelial growth factor A Mus musculus 26-30 26061387-8 2015 DHI improved renal functions by inhibiting mesangial matrix expansion, expression of vascular endothelial growth factor A, fibronectin and advanced glycation end products in kidneys. dehydrosoyasaponin I 0-3 vascular endothelial growth factor A Mus musculus 85-121 30093864-9 2018 Additionally, MSC in combination with DHI interfered with MI in mice and this signifies that when combined, the duo could the expression of vascular endothelial growth factor (VEGF) in the marginal zone of infarction compared with when either MSC or DHI are used individually. dehydrosoyasaponin I 38-41 vascular endothelial growth factor A Mus musculus 140-174 30093864-9 2018 Additionally, MSC in combination with DHI interfered with MI in mice and this signifies that when combined, the duo could the expression of vascular endothelial growth factor (VEGF) in the marginal zone of infarction compared with when either MSC or DHI are used individually. dehydrosoyasaponin I 38-41 vascular endothelial growth factor A Mus musculus 176-180 27930695-8 2016 DHI administration upregulated the expression of vascular endothelial growth factor A (VEGF-A) and VEGF receptor-2 (VEGFR-2) in ischemic muscle. dehydrosoyasaponin I 0-3 vascular endothelial growth factor A Mus musculus 49-85 27930695-8 2016 DHI administration upregulated the expression of vascular endothelial growth factor A (VEGF-A) and VEGF receptor-2 (VEGFR-2) in ischemic muscle. dehydrosoyasaponin I 0-3 vascular endothelial growth factor A Mus musculus 87-93 27930695-10 2016 We confirmed that upregulation of VEGF-A/VEGFR-2 by DHI promoted PPARdelta gene expression in both type 2 diabetic mice. dehydrosoyasaponin I 52-55 vascular endothelial growth factor A Mus musculus 34-40 27930695-11 2016 Our findings demonstrated that a multi-component Chinese medicine DHI effectively increased blood flow recovery after tissue ischemia in diabetic mice by promoting angiogenesis and improving glucose tolerance through a concomitant activation of VEGF-A/VEGFR-2 and PPARdelta signaling pathways. dehydrosoyasaponin I 66-69 vascular endothelial growth factor A Mus musculus 245-251