PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23458896-4	2013	However, at a low concentration (1 muM) where neither 1-NP, 1-AP nor unsubstituted pyrene had any effect on chemokine responses, we found that all three PAHs potentiated CXCL8 and CCL5 responses induced by the TLR3 ligand polyinosinic:polycytidylic acid (Poly I:C) in BEAS-2B cells.	Polycyclic Aromatic Hydrocarbons	153-157	C-X-C motif chemokine ligand 8	Homo sapiens	170-175	
24811947-6	2014	The releases of IL-8 from A549 and TNF-alpha from J774A.1 were significantly correlated to PM size, Zeta potential, endotoxin, major metals, and polycyclic aromatic hydrocarbons.	Polycyclic Aromatic Hydrocarbons	145-177	C-X-C motif chemokine ligand 8	Homo sapiens	16-20	
16497101-10	2006	Chemokine pathway (IL-8) and TNF-alpha activity seem to be modulated by Goeckerman"s therapy (polycyclic aromatic hydrocarbons).	Polycyclic Aromatic Hydrocarbons	94-126	C-X-C motif chemokine ligand 8	Homo sapiens	19-23	
18830893-5	2008	PAH induced significant secretion of IL-1beta, IL-8, and IL-12 after 24 or 48 hr of treatment, an effect reinforced by LPS stimulation; no effect on IL-10 secretion was noted.	Polycyclic Aromatic Hydrocarbons	0-3	C-X-C motif chemokine ligand 8	Homo sapiens	47-51	
18035981-10	2007	This fact indicates that the chemokine pathway of IL-8 activity could be modulated by this treatment, most likely by polycyclic aromatic hydrocarbons.	Polycyclic Aromatic Hydrocarbons	117-149	C-X-C motif chemokine ligand 8	Homo sapiens	50-54	
32464779-4	2020	Urinary metabolites of PAHs (i.e., OH-PAHs), measured as indicators of total PAH exposure, showed significant associations with markers of respiratory and systemic inflammation, including exhaled nitric oxide, interleukin (IL)-6 in exhaled breath condensate, and blood IL-2 and IL-8 levels and leucocyte count.	Polycyclic Aromatic Hydrocarbons	23-26	C-X-C motif chemokine ligand 8	Homo sapiens	278-282	
12946434-3	2003	We have characterized the influence of pyrene, a polycyclic aromatic hydrocarbon (PAH) contained, for example, in diesel exhaust particles (DEP), on transcription and secretion of the chemokines interleukin-8 (IL-8) and eotaxin.	Polycyclic Aromatic Hydrocarbons	49-80	C-X-C motif chemokine ligand 8	Homo sapiens	195-208	
12946434-3	2003	We have characterized the influence of pyrene, a polycyclic aromatic hydrocarbon (PAH) contained, for example, in diesel exhaust particles (DEP), on transcription and secretion of the chemokines interleukin-8 (IL-8) and eotaxin.	Polycyclic Aromatic Hydrocarbons	82-85	C-X-C motif chemokine ligand 8	Homo sapiens	195-208	
12393170-0	2002	Polycyclic aromatic hydrocarbons induce IL-8 expression through nuclear factor kappaB activation in A549 cell line.	Polycyclic Aromatic Hydrocarbons	0-32	C-X-C motif chemokine ligand 8	Homo sapiens	40-44	
12393170-5	2002	However, it is unknown whether polycyclic aromatic hydrocarbons (PAH), mainly existed in most airborne particulates, can separately induce IL-8 expression.	Polycyclic Aromatic Hydrocarbons	31-63	C-X-C motif chemokine ligand 8	Homo sapiens	139-143	
12393170-5	2002	However, it is unknown whether polycyclic aromatic hydrocarbons (PAH), mainly existed in most airborne particulates, can separately induce IL-8 expression.	Polycyclic Aromatic Hydrocarbons	65-68	C-X-C motif chemokine ligand 8	Homo sapiens	139-143	
12393170-6	2002	In the present study, we investigated the effect of benzo(a)pyrene (B[a]P) and 1-nitropyrene (1-NP), two representative PAH, on IL-8 expression using ELISA and Northern blot analysis.	Polycyclic Aromatic Hydrocarbons	120-123	C-X-C motif chemokine ligand 8	Homo sapiens	128-132	
12393170-8	2002	We have assessed the effect of adenovirus-mediated overexpression of the NF-kappaB inhibitor, IkappaBalpha on PAH-induced IL-8 expression in A549 cell line.	Polycyclic Aromatic Hydrocarbons	110-113	C-X-C motif chemokine ligand 8	Homo sapiens	122-126	
12393170-12	2002	This suggests that PAH-induced IL-8 gene regulation may be mediated by NF-kappaB.	Polycyclic Aromatic Hydrocarbons	19-22	C-X-C motif chemokine ligand 8	Homo sapiens	31-35	
12393170-13	2002	These data indicate that PAH alone, either B[a]P or 1-NP, is sufficient to stimulate NF-kappaB activation and IL-8 transcription.	Polycyclic Aromatic Hydrocarbons	25-28	C-X-C motif chemokine ligand 8	Homo sapiens	110-114