PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9725235-3	1998	In this study we demonstrate that stimulation of IFN-alpha synthesis by HSV is inhibited by a number of monosaccharides, including fucose, N-acetylglucosamine, and N-acetylgalactosamine as well as the yeast polysaccharide mannan, supporting a role for lectin(s) in the IFN-alpha stimulation pathway.	Polysaccharides	207-221	interferon alpha 1	Homo sapiens	49-58	
10213468-0	1999	Simple mixing of IFN with a polysaccharide having high liver affinity enables IFN to target to the liver.	Polysaccharides	28-42	interferon alpha 1	Homo sapiens	78-81	
9587963-10	1998	Crystallographic data for IFN-beta-1a revealed that the glycan formed H-bonds with the peptide backbone and shielded an uncharged surface from solvent exposure.	Polysaccharides	56-62	interferon alpha 1	Homo sapiens	26-29	
6190759-8	1983	IFN inducers (polyinosinic acid-polycytidylic acid, 6-MFA [a mixture of proteins, polysaccharides, and double-stranded DNA isolated from Aspergillus ochraceus ATCC 28706]) protected a significant number of mice against SFV infection.	Polysaccharides	82-97	interferon alpha 1	Homo sapiens	0-3	
32827942-7	2020	Examining cell-surface glycomes, IFNalpha increases levels of the immunosuppressive GalNAc-containing glycans (T/Tn antigens) on CD8+ T cells.	Polysaccharides	102-109	interferon alpha 1	Homo sapiens	33-41	
22230586-4	2012	We demonstrate below that in immune responses to the diptheria/acellular pertussis/tetanus and pneumococcal polysaccharide conjugate vaccines, potentially antagonistic Th1-/IFN-associated and Th2-associated gene networks coexist in an apparent state of dynamic equilibrium, whereas in Th2-dominant allergen-specific responses of atopics the Th1 and IFN networks are respectively disrupted and downregulated.	Polysaccharides	108-122	interferon alpha 1	Homo sapiens	173-176	
7506267-6	1993	Upregulation of L-selectin surface density in IFN-alpha-treated Daudi B cells correlated directly with an increase in L-selectin mRNA steady state levels and enhanced L-selectin-dependent binding to a carbohydrate-based ligand, phosphomonoester core polysaccharide.	Polysaccharides	250-264	interferon alpha 1	Homo sapiens	46-55	
27847204-4	2016	By using ELISA and western blot assay, the expression level of IFN-alpha and IRF3 and their functional roles in polysaccharide-mediated antiviral activity against RSV were investigated.	Polysaccharides	112-126	interferon alpha 1	Homo sapiens	63-72	
27847204-8	2016	The polysaccharide extract improved IRF-3 expression which promoted the level of IFN-alpha.	Polysaccharides	4-18	interferon alpha 1	Homo sapiens	81-90	
27847204-9	2016	IN CONCLUSION: Polysaccharide extract from Laminaria japonica elicits antiviral activity against RSV by up-regulation of IRF3 signaling-mediated IFN-alpha production.	Polysaccharides	15-29	interferon alpha 1	Homo sapiens	145-154