PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 6190759-8 1983 IFN inducers (polyinosinic acid-polycytidylic acid, 6-MFA [a mixture of proteins, polysaccharides, and double-stranded DNA isolated from Aspergillus ochraceus ATCC 28706]) protected a significant number of mice against SFV infection. Polysaccharides 82-97 interferon alpha 1 Homo sapiens 0-3 32827942-7 2020 Examining cell-surface glycomes, IFNalpha increases levels of the immunosuppressive GalNAc-containing glycans (T/Tn antigens) on CD8+ T cells. Polysaccharides 102-109 interferon alpha 1 Homo sapiens 33-41 27847204-4 2016 By using ELISA and western blot assay, the expression level of IFN-alpha and IRF3 and their functional roles in polysaccharide-mediated antiviral activity against RSV were investigated. Polysaccharides 112-126 interferon alpha 1 Homo sapiens 63-72 27847204-8 2016 The polysaccharide extract improved IRF-3 expression which promoted the level of IFN-alpha. Polysaccharides 4-18 interferon alpha 1 Homo sapiens 81-90 27847204-9 2016 IN CONCLUSION: Polysaccharide extract from Laminaria japonica elicits antiviral activity against RSV by up-regulation of IRF3 signaling-mediated IFN-alpha production. Polysaccharides 15-29 interferon alpha 1 Homo sapiens 145-154 22230586-4 2012 We demonstrate below that in immune responses to the diptheria/acellular pertussis/tetanus and pneumococcal polysaccharide conjugate vaccines, potentially antagonistic Th1-/IFN-associated and Th2-associated gene networks coexist in an apparent state of dynamic equilibrium, whereas in Th2-dominant allergen-specific responses of atopics the Th1 and IFN networks are respectively disrupted and downregulated. Polysaccharides 108-122 interferon alpha 1 Homo sapiens 173-176 10213468-0 1999 Simple mixing of IFN with a polysaccharide having high liver affinity enables IFN to target to the liver. Polysaccharides 28-42 interferon alpha 1 Homo sapiens 78-81 9725235-3 1998 In this study we demonstrate that stimulation of IFN-alpha synthesis by HSV is inhibited by a number of monosaccharides, including fucose, N-acetylglucosamine, and N-acetylgalactosamine as well as the yeast polysaccharide mannan, supporting a role for lectin(s) in the IFN-alpha stimulation pathway. Polysaccharides 207-221 interferon alpha 1 Homo sapiens 49-58 9587963-10 1998 Crystallographic data for IFN-beta-1a revealed that the glycan formed H-bonds with the peptide backbone and shielded an uncharged surface from solvent exposure. Polysaccharides 56-62 interferon alpha 1 Homo sapiens 26-29 7506267-6 1993 Upregulation of L-selectin surface density in IFN-alpha-treated Daudi B cells correlated directly with an increase in L-selectin mRNA steady state levels and enhanced L-selectin-dependent binding to a carbohydrate-based ligand, phosphomonoester core polysaccharide. Polysaccharides 250-264 interferon alpha 1 Homo sapiens 46-55