PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34787621-0 2021 Potential interference of graphene nanosheets in immune response via disrupting the recognition of HLA-presented KK10 by TCR: a molecular dynamics simulation study. Graphite 26-34 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 121-124 34787621-4 2021 For the illustrated human immunodeficiency virus (HIV) antigen peptide KK10, human leukocyte antigen (HLA), and T cell receptor (TCR) ternary complex, we found that the graphene nanosheet could disrupt the critical protein-protein interactions between TCR and peptide-HLA and impair the antigen recognition by TCR, leaving the antigen presentation unaffected. Graphite 169-177 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 112-127 34787621-4 2021 For the illustrated human immunodeficiency virus (HIV) antigen peptide KK10, human leukocyte antigen (HLA), and T cell receptor (TCR) ternary complex, we found that the graphene nanosheet could disrupt the critical protein-protein interactions between TCR and peptide-HLA and impair the antigen recognition by TCR, leaving the antigen presentation unaffected. Graphite 169-177 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 129-132 34787621-4 2021 For the illustrated human immunodeficiency virus (HIV) antigen peptide KK10, human leukocyte antigen (HLA), and T cell receptor (TCR) ternary complex, we found that the graphene nanosheet could disrupt the critical protein-protein interactions between TCR and peptide-HLA and impair the antigen recognition by TCR, leaving the antigen presentation unaffected. Graphite 169-177 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 252-255 34787621-4 2021 For the illustrated human immunodeficiency virus (HIV) antigen peptide KK10, human leukocyte antigen (HLA), and T cell receptor (TCR) ternary complex, we found that the graphene nanosheet could disrupt the critical protein-protein interactions between TCR and peptide-HLA and impair the antigen recognition by TCR, leaving the antigen presentation unaffected. Graphite 169-177 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 310-313 34787621-5 2021 Moreover, the hydrophobic interaction and van der Waals potential energy collectively drive the spontaneous separation of TCR from the peptide-HLA complex by graphene nanosheets. Graphite 158-166 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 122-125 28805869-8 2017 For this layered model, the quantitative analysis by classical theories demonstrates the suitable thickness ratio of graphene layer and metal layer to achieve zero TCR to be 0.2, agreeing well with our experimental results. Graphite 117-125 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 164-167 28805869-9 2017 This wrinkle-stabilized approach and our theoretical analysis of zero-TCR behavior of the graphene-metal system are conducive to the design of high-performance conducting materials based on graphene and metals. Graphite 90-98 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 70-73 28805869-9 2017 This wrinkle-stabilized approach and our theoretical analysis of zero-TCR behavior of the graphene-metal system are conducive to the design of high-performance conducting materials based on graphene and metals. Graphite 190-198 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 70-73