PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33455332-0 2020 Effects of the Hydrophobicity of Key Residues on the Characteristics and Stability of Glucose Oxidase on a Graphene Surface. Graphite 107-115 hydroxyacid oxidase 1 Homo sapiens 86-101 33455332-4 2020 To develop a hybrid enzyme-graphene nanodevice with a good performance, it is important that GOx is deposited well on the graphene surface while maintaining its structure and not impeding the oxidation activity of the GOx. Graphite 27-35 hydroxyacid oxidase 1 Homo sapiens 93-96 33455332-4 2020 To develop a hybrid enzyme-graphene nanodevice with a good performance, it is important that GOx is deposited well on the graphene surface while maintaining its structure and not impeding the oxidation activity of the GOx. Graphite 27-35 hydroxyacid oxidase 1 Homo sapiens 218-221 33455332-4 2020 To develop a hybrid enzyme-graphene nanodevice with a good performance, it is important that GOx is deposited well on the graphene surface while maintaining its structure and not impeding the oxidation activity of the GOx. Graphite 122-130 hydroxyacid oxidase 1 Homo sapiens 93-96 33455332-5 2020 In this study, we propose a method to improve the stability of GOx and secure its immobility on the graphene sheet and its glucose-binding affinity by single-point mutation of GOx using molecular dynamics simulations. Graphite 100-108 hydroxyacid oxidase 1 Homo sapiens 63-66 33455332-5 2020 In this study, we propose a method to improve the stability of GOx and secure its immobility on the graphene sheet and its glucose-binding affinity by single-point mutation of GOx using molecular dynamics simulations. Graphite 100-108 hydroxyacid oxidase 1 Homo sapiens 176-179 27524075-6 2016 The use of graphene in the immobilization of GOx promoted Direct Electron Transfer, which was evaluated by Cyclic Voltammetry. Graphite 11-19 hydroxyacid oxidase 1 Homo sapiens 45-48 31546385-0 2019 Glucose oxidase immobilized amine terminated multiwall carbon nanotubes/reduced graphene oxide/polyaniline/gold nanoparticles modified screen-printed carbon electrode for highly sensitive amperometric glucose detection. Graphite 80-94 hydroxyacid oxidase 1 Homo sapiens 0-15 31664095-1 2019 State-of-the-art ultra-sensitive blood glucose-monitoring biosensors, based on glucose oxidase (GOx) covalently linked to a single layer graphene (SLG), will be a valuable next generation diagnostic tool for personal glycemic level management. Graphite 137-145 hydroxyacid oxidase 1 Homo sapiens 96-99 31664095-2 2019 We report here our observations of sensor matrix structure obtained using a multi-physics approach towards analysis of small-angle neutron scattering (SANS) on graphene-based biosensor functionalized with GOx under different pH conditions for various hierarchical GOx assemblies within SLG. Graphite 160-168 hydroxyacid oxidase 1 Homo sapiens 205-208 31664095-2 2019 We report here our observations of sensor matrix structure obtained using a multi-physics approach towards analysis of small-angle neutron scattering (SANS) on graphene-based biosensor functionalized with GOx under different pH conditions for various hierarchical GOx assemblies within SLG. Graphite 160-168 hydroxyacid oxidase 1 Homo sapiens 264-267 30870640-3 2019 We report here for the first time, a low cost lab-on-a-screen-printed electrochemical cell (SPC) based on iron-sparked graphite working electrode modified with glucose oxidase (GOx) and glucose hydrogel droplets (GluHD) for the detection of flunitrazepam. Graphite 119-127 hydroxyacid oxidase 1 Homo sapiens 160-175 30870640-3 2019 We report here for the first time, a low cost lab-on-a-screen-printed electrochemical cell (SPC) based on iron-sparked graphite working electrode modified with glucose oxidase (GOx) and glucose hydrogel droplets (GluHD) for the detection of flunitrazepam. Graphite 119-127 hydroxyacid oxidase 1 Homo sapiens 177-180 31664095-1 2019 State-of-the-art ultra-sensitive blood glucose-monitoring biosensors, based on glucose oxidase (GOx) covalently linked to a single layer graphene (SLG), will be a valuable next generation diagnostic tool for personal glycemic level management. Graphite 137-145 hydroxyacid oxidase 1 Homo sapiens 79-94 31632005-5 2019 Methods: Herein, the investigators modified the interdigitated (di)electrodes (IDE) sensing surface to detect the glucose on covalently immobilized glucose oxidase (GOx) with the graphene. Graphite 179-187 hydroxyacid oxidase 1 Homo sapiens 148-163 31632005-5 2019 Methods: Herein, the investigators modified the interdigitated (di)electrodes (IDE) sensing surface to detect the glucose on covalently immobilized glucose oxidase (GOx) with the graphene. Graphite 179-187 hydroxyacid oxidase 1 Homo sapiens 165-168 30616214-6 2019 The tested graphene materials doped with ferrocene moieties were used as a bioactive platform for glucose oxidase (GOx) immobilization. Graphite 11-19 hydroxyacid oxidase 1 Homo sapiens 98-113 30616214-6 2019 The tested graphene materials doped with ferrocene moieties were used as a bioactive platform for glucose oxidase (GOx) immobilization. Graphite 11-19 hydroxyacid oxidase 1 Homo sapiens 115-118 30616214-8 2019 Ferrocene moieties present at the graphene surface play the role of mediator in the electron transfer between the redox center of GOx and the electrode surface. Graphite 34-42 hydroxyacid oxidase 1 Homo sapiens 130-133 30412378-8 2018 The GOx-loaded microcapsules were immobilized on a variety of surfaces (here, inside a flow channel, on a carbon-coated sensor or a graphite rod) and glucose concentrations up to 10 mM could successfully be measured. Graphite 132-140 hydroxyacid oxidase 1 Homo sapiens 4-7 28551130-0 2017 Reagent-less amperometric glucose biosensor based on a graphite rod electrode layer-by-layer modified with 1,10-phenanthroline-5,6-dione and glucose oxidase. Graphite 55-63 hydroxyacid oxidase 1 Homo sapiens 141-156 27524025-6 2016 The triethylenetetramine-functionalized graphene was then applied to fabricate glucose biosensors with IO4(-) oxidized glucose oxidase (GOx) through layer-by-layer (LBL) self-assembly by the covalent bonding between the aldehyde groups of GOx and amino groups of TFGn. Graphite 40-48 hydroxyacid oxidase 1 Homo sapiens 119-134 27524025-6 2016 The triethylenetetramine-functionalized graphene was then applied to fabricate glucose biosensors with IO4(-) oxidized glucose oxidase (GOx) through layer-by-layer (LBL) self-assembly by the covalent bonding between the aldehyde groups of GOx and amino groups of TFGn. Graphite 40-48 hydroxyacid oxidase 1 Homo sapiens 136-139 27524025-6 2016 The triethylenetetramine-functionalized graphene was then applied to fabricate glucose biosensors with IO4(-) oxidized glucose oxidase (GOx) through layer-by-layer (LBL) self-assembly by the covalent bonding between the aldehyde groups of GOx and amino groups of TFGn. Graphite 40-48 hydroxyacid oxidase 1 Homo sapiens 239-242 28809354-1 2013 : A simple procedure was developed for the fabrication of electrochemical glucose biosensors using glucose oxidase (GOx), with graphene or multi-walled carbon nanotubes (MWCNTs). Graphite 127-135 hydroxyacid oxidase 1 Homo sapiens 99-114 26551320-0 2015 Electrochemically Functionalized Seamless Three-Dimensional Graphene-Carbon Nanotube Hybrid for Direct Electron Transfer of Glucose Oxidase and Bioelectrocatalysis. Graphite 60-68 hydroxyacid oxidase 1 Homo sapiens 124-139 26551320-1 2015 Three-dimensional seamless chemical vapor deposition (CVD) grown graphene-carbon nanotubes (G-CNT) hybrid film has been studied for its potential in achieving direct electron transfer (DET) of glucose oxidase (GOx) and its bioelectrocatalytic activity in glucose detection. Graphite 65-73 hydroxyacid oxidase 1 Homo sapiens 193-208 26551320-1 2015 Three-dimensional seamless chemical vapor deposition (CVD) grown graphene-carbon nanotubes (G-CNT) hybrid film has been studied for its potential in achieving direct electron transfer (DET) of glucose oxidase (GOx) and its bioelectrocatalytic activity in glucose detection. Graphite 65-73 hydroxyacid oxidase 1 Homo sapiens 210-213 26215343-0 2015 Glucose biosensor based on glucose oxidase immobilized at gold nanoparticles decorated graphene-carbon nanotubes. Graphite 87-95 hydroxyacid oxidase 1 Homo sapiens 27-42 25796041-2 2015 In this construction strategy, the nanocomposites of three-dimensional graphene and gold nanoparticles (3D-GR-AuNPs) were used as matrix for high loading of glucose oxidase (GOx), which served as recognition element for bounding Con A. Con A further interacted with DexP-g-C3N4 through a specific carbohydrate-Con A interaction to achieve a sandwiched scheme. Graphite 71-79 hydroxyacid oxidase 1 Homo sapiens 157-172 25433682-1 2015 A highly sensitive electrochemiluminescent (ECL) biosensor was designed for the detection of concanavalin A (ConA) based on glucose oxidase (GOx) as a recognition element by carbohydrate-lectin biospecific interaction, and poly(ethylenimine) (PEI) reduced graphene and hollow gold nanoparticles (HAuNPs) as supporting matrix and signal amplifier. Graphite 256-264 hydroxyacid oxidase 1 Homo sapiens 124-139 25433682-1 2015 A highly sensitive electrochemiluminescent (ECL) biosensor was designed for the detection of concanavalin A (ConA) based on glucose oxidase (GOx) as a recognition element by carbohydrate-lectin biospecific interaction, and poly(ethylenimine) (PEI) reduced graphene and hollow gold nanoparticles (HAuNPs) as supporting matrix and signal amplifier. Graphite 256-264 hydroxyacid oxidase 1 Homo sapiens 141-144 25454754-1 2014 This study is focused on the investigation of electrocatalytic effect of glucose oxidase (GOx) immobilized on the graphite rod (GR) electrode. Graphite 114-122 hydroxyacid oxidase 1 Homo sapiens 73-88 25454754-1 2014 This study is focused on the investigation of electrocatalytic effect of glucose oxidase (GOx) immobilized on the graphite rod (GR) electrode. Graphite 114-122 hydroxyacid oxidase 1 Homo sapiens 90-93 25248701-0 2014 Immobilization of glucose oxidase on graphene and cobalt phthalocyanine composite and its application for the determination of glucose. Graphite 37-45 hydroxyacid oxidase 1 Homo sapiens 18-33 23973906-3 2013 To fabricate the desired biosensor, glucose oxidase (GOx) was immobilized as a model enzyme on the polymer coated graphite electrode with the help of glutaraldehyde (GA). Graphite 114-122 hydroxyacid oxidase 1 Homo sapiens 36-51 23973906-3 2013 To fabricate the desired biosensor, glucose oxidase (GOx) was immobilized as a model enzyme on the polymer coated graphite electrode with the help of glutaraldehyde (GA). Graphite 114-122 hydroxyacid oxidase 1 Homo sapiens 53-56 32263308-0 2016 Preparation of graphene nano-sheet bonded PDA/MOF microcapsules with immobilized glucose oxidase as a mimetic multi-enzyme system for electrochemical sensing of glucose. Graphite 15-23 hydroxyacid oxidase 1 Homo sapiens 81-96 25686953-1 2015 In the present work we report a facile method for fabrication of glucose oxidase immobilized on the partially reduced graphene-gold nanocomposite (PRGO-AuNPs/GOx) as a novel biosensor for determination of glucose concentration. Graphite 118-126 hydroxyacid oxidase 1 Homo sapiens 158-161 25435508-0 2015 Development of glucose biosensor based on reconstitution of glucose oxidase onto polymeric redox mediator coated pencil graphite electrodes. Graphite 120-128 hydroxyacid oxidase 1 Homo sapiens 60-75 25435508-1 2015 In this study, a novel glucose biosensor was fabricated by reconstitutional immobilization of glucose oxidase (GOx) onto a poly(glycidyl methacrylate-co-vinylferrocene) (poly(GMA-co-VFc)) film coated pencil graphite electrode (PGE). Graphite 207-215 hydroxyacid oxidase 1 Homo sapiens 94-109 25435508-1 2015 In this study, a novel glucose biosensor was fabricated by reconstitutional immobilization of glucose oxidase (GOx) onto a poly(glycidyl methacrylate-co-vinylferrocene) (poly(GMA-co-VFc)) film coated pencil graphite electrode (PGE). Graphite 207-215 hydroxyacid oxidase 1 Homo sapiens 111-114 23486775-1 2013 The fabrication of glucose oxidase (GOx) enzyme electrodes with controlled alternate enzyme and graphene layers is described. Graphite 96-104 hydroxyacid oxidase 1 Homo sapiens 19-34 23486775-1 2013 The fabrication of glucose oxidase (GOx) enzyme electrodes with controlled alternate enzyme and graphene layers is described. Graphite 96-104 hydroxyacid oxidase 1 Homo sapiens 36-39 23486775-2 2013 GOx was first modified with pyrene functionalities in order to be self-assembled onto a graphene basal plane via non-covalent pi-pi stacking interaction. Graphite 88-96 hydroxyacid oxidase 1 Homo sapiens 0-3 23098855-0 2013 Graphene quantum dots as a new substrate for immobilization and direct electrochemistry of glucose oxidase: application to sensitive glucose determination. Graphite 0-8 hydroxyacid oxidase 1 Homo sapiens 91-106 28809354-1 2013 : A simple procedure was developed for the fabrication of electrochemical glucose biosensors using glucose oxidase (GOx), with graphene or multi-walled carbon nanotubes (MWCNTs). Graphite 127-135 hydroxyacid oxidase 1 Homo sapiens 116-119 28809354-3 2013 The EDC (1-ethyl-(3-dimethylaminopropyl) carbodiimide)-activated GOx was then bound covalently on the graphene- or MWCNT-modified GCE. Graphite 102-110 hydroxyacid oxidase 1 Homo sapiens 65-68 21513282-4 2011 On the basis of the cathodic ECL signal of luminol on the graphene-modified electrode, an ECL sandwich immunosensor for sensitive detection of cancer biomarkers at low potential was developed with a multiple signal amplification strategy from functionalized graphene and gold nanorods multilabeled with glucose oxidase (GOx) and secondary antibody (Ab(2)). Graphite 58-66 hydroxyacid oxidase 1 Homo sapiens 303-318 22967516-1 2012 A mediatorless glucose biosensor was developed by the immobilization of glucose oxidase (GOx) to graphene-functionalized glassy carbon electrode (GCE). Graphite 97-105 hydroxyacid oxidase 1 Homo sapiens 72-87 22967516-1 2012 A mediatorless glucose biosensor was developed by the immobilization of glucose oxidase (GOx) to graphene-functionalized glassy carbon electrode (GCE). Graphite 97-105 hydroxyacid oxidase 1 Homo sapiens 89-92 22967516-3 2012 This was followed by the covalent binding of GOx to graphene-functionalized GCE using 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride (EDC) based crosslinking. Graphite 52-60 hydroxyacid oxidase 1 Homo sapiens 45-48 22967516-4 2012 Graphene provided signal enhancement by providing greater surface area for GOx binding, while APTES-functionalization led to a higher GOx immobilization density by providing free amino groups for crosslinking. Graphite 0-8 hydroxyacid oxidase 1 Homo sapiens 75-78 22967516-9 2012 The developed bioanalytical procedure for preparation of GOx-bound graphene-functionalized GCEs had high production reproducibility and high storage stability, which is appropriate for the commercial mass production of enzyme-bound electrodes. Graphite 67-75 hydroxyacid oxidase 1 Homo sapiens 57-60 21513282-4 2011 On the basis of the cathodic ECL signal of luminol on the graphene-modified electrode, an ECL sandwich immunosensor for sensitive detection of cancer biomarkers at low potential was developed with a multiple signal amplification strategy from functionalized graphene and gold nanorods multilabeled with glucose oxidase (GOx) and secondary antibody (Ab(2)). Graphite 58-66 hydroxyacid oxidase 1 Homo sapiens 320-323 16245530-5 2005 The results obtained favorably compare to those of a glucose biosensor based on a graphite epoxy composite (GOx-GEC). Graphite 82-90 hydroxyacid oxidase 1 Homo sapiens 108-111 20605713-4 2010 Bioelectrochemical responses of PDs and glucose oxidase (GOX)-modified graphite rod electrodes (GREs) were studied amperometrically and potentiometrically. Graphite 71-79 hydroxyacid oxidase 1 Homo sapiens 40-55 20605713-4 2010 Bioelectrochemical responses of PDs and glucose oxidase (GOX)-modified graphite rod electrodes (GREs) were studied amperometrically and potentiometrically. Graphite 71-79 hydroxyacid oxidase 1 Homo sapiens 57-60 19594172-2 2009 The compatibility of a graphite electrode modified by these peptide nanofibers with enzymes is demonstrated using a model enzyme glucose oxidase (GOx). Graphite 23-31 hydroxyacid oxidase 1 Homo sapiens 129-144 19594172-2 2009 The compatibility of a graphite electrode modified by these peptide nanofibers with enzymes is demonstrated using a model enzyme glucose oxidase (GOx). Graphite 23-31 hydroxyacid oxidase 1 Homo sapiens 146-149 18457943-4 2008 The marked electrocatalytic activity towards hydrogen peroxide permits effective amperometric biosensing of glucose in connection with the incorporation of glucose oxidase within the three-dimensional IL/graphite matrix. Graphite 204-212 hydroxyacid oxidase 1 Homo sapiens 156-171 17113278-1 2007 Glucose sensing electrodes have been realized by immobilizing glucose oxidase (GOx) on unmodified edge plane of highly oriented pyrolytic graphite (epHOPG) and the native oxide of heavily doped silicon (SiO2/Si). Graphite 138-146 hydroxyacid oxidase 1 Homo sapiens 62-77 17113278-1 2007 Glucose sensing electrodes have been realized by immobilizing glucose oxidase (GOx) on unmodified edge plane of highly oriented pyrolytic graphite (epHOPG) and the native oxide of heavily doped silicon (SiO2/Si). Graphite 138-146 hydroxyacid oxidase 1 Homo sapiens 79-82 16245530-4 2005 Experimental results show that the CNT epoxy composite biosensor (GOx-CNTEC) offers an excellent sensitivity, reliable calibration profile, and stable electrochemical properties together with significantly lower detection potential (+0.55 V) than GOx-graphite epoxy composites (+0.90 V; difference deltaE = 0.35 V). Graphite 251-259 hydroxyacid oxidase 1 Homo sapiens 66-69 18970008-1 2005 The performance of amperometric glucose biosensors based on the dispersion of glucose oxidase (GOx) and copper oxide within a classical carbon (graphite) paste composite is reported in this work. Graphite 144-152 hydroxyacid oxidase 1 Homo sapiens 78-93 18970008-1 2005 The performance of amperometric glucose biosensors based on the dispersion of glucose oxidase (GOx) and copper oxide within a classical carbon (graphite) paste composite is reported in this work. Graphite 144-152 hydroxyacid oxidase 1 Homo sapiens 95-98 35149425-6 2022 Then, the molecularly imprinted GOx are immobilized on the surface of highly oriented pyrolytic graphite (HOPG) electrode and an electrochemical biosensor (Fe3O4@Au-GOx-HOPG) for glucose sensing is successfully obtained. Graphite 96-104 hydroxyacid oxidase 1 Homo sapiens 32-35 34436075-2 2021 Here, we studied the effect of DNA adsorption on electrochemical charge transfer at few-layered, oxygen-functionalized graphene (GOx) electrodes. Graphite 119-127 hydroxyacid oxidase 1 Homo sapiens 129-132 34436069-2 2021 We investigated the immobilization of glucose oxidase (GOx) on a new composite nanomaterial poly(3,4-ethylenedioxythiophene): polystyrene sulfonate (PEDOT:PSS)/titanium carbide,(Ti3C2)/graphene quantum dots(GQD) modified screen-printed carbon electrode (SPCE) for glucose sensing. Graphite 185-193 hydroxyacid oxidase 1 Homo sapiens 38-53 34436069-2 2021 We investigated the immobilization of glucose oxidase (GOx) on a new composite nanomaterial poly(3,4-ethylenedioxythiophene): polystyrene sulfonate (PEDOT:PSS)/titanium carbide,(Ti3C2)/graphene quantum dots(GQD) modified screen-printed carbon electrode (SPCE) for glucose sensing. Graphite 185-193 hydroxyacid oxidase 1 Homo sapiens 55-58 34385012-3 2021 This nanosensor is prepared through the in-situ growth of silver nanoparticles (AgNPs) with the synergetic reduction of tannic acid (TA) and graphene quantum dots (GQDs), which are further decorated with glucose oxidase (GOx). Graphite 141-149 hydroxyacid oxidase 1 Homo sapiens 204-219 34385012-3 2021 This nanosensor is prepared through the in-situ growth of silver nanoparticles (AgNPs) with the synergetic reduction of tannic acid (TA) and graphene quantum dots (GQDs), which are further decorated with glucose oxidase (GOx). Graphite 141-149 hydroxyacid oxidase 1 Homo sapiens 221-224 35458293-4 2022 It was shown that, from the point of view of both the rate of electron transfer to the electrode, and the rate of interaction with the active center of glucose oxidase (GOx), the most promising is a new nanocomposite based on poly(neutral red) (pNR) and thermally expanded graphite (TEG). Graphite 273-281 hydroxyacid oxidase 1 Homo sapiens 152-167 35458293-4 2022 It was shown that, from the point of view of both the rate of electron transfer to the electrode, and the rate of interaction with the active center of glucose oxidase (GOx), the most promising is a new nanocomposite based on poly(neutral red) (pNR) and thermally expanded graphite (TEG). Graphite 273-281 hydroxyacid oxidase 1 Homo sapiens 169-172 32573601-0 2020 A 3D porous graphene aerogel@GOx based microfluidic biosensor for electrochemical glucose detection. Graphite 12-20 hydroxyacid oxidase 1 Homo sapiens 29-32 32573601-3 2020 In this paper, an enzymatic electrochemical microfluidic biosensor for glucose detection was developed based on a three-dimensional (3D) porous graphene aerogel and glucose oxidase (GOx). Graphite 144-152 hydroxyacid oxidase 1 Homo sapiens 182-185 32573601-4 2020 A graphene aerogel was prepared by freeze-drying a graphene hydrogel and has a high electrical conductivity, the 3D porous structure provided a good near-biological condition for GOx and the increased specific surface area allowed more GOx to be immobilized on the graphene aerogel. Graphite 2-10 hydroxyacid oxidase 1 Homo sapiens 179-182 32573601-4 2020 A graphene aerogel was prepared by freeze-drying a graphene hydrogel and has a high electrical conductivity, the 3D porous structure provided a good near-biological condition for GOx and the increased specific surface area allowed more GOx to be immobilized on the graphene aerogel. Graphite 2-10 hydroxyacid oxidase 1 Homo sapiens 236-239