PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21149572-1 2011 Cbf5 is the catalytic subunit of the H/ACA small nucleolar/Cajal body ribonucleoprotein particles (RNPs) responsible for site specific isomerization of uridine in ribosomal and small nuclear RNA. Uridine 152-159 dyskerin pseudouridine synthase 1 Homo sapiens 0-4 22993689-1 2012 Cbf5 is a pseudouridine synthase that usually acts in a guide RNA-dependent manner as part of H/ACA small ribonucleoproteins; however archaeal Cbf5 can also act independently of guide RNA in modifying uridine 55 in tRNA. Uridine 16-23 dyskerin pseudouridine synthase 1 Homo sapiens 0-4 22993689-1 2012 Cbf5 is a pseudouridine synthase that usually acts in a guide RNA-dependent manner as part of H/ACA small ribonucleoproteins; however archaeal Cbf5 can also act independently of guide RNA in modifying uridine 55 in tRNA. Uridine 16-23 dyskerin pseudouridine synthase 1 Homo sapiens 143-147 19481523-1 2009 H/ACA RNAs form ribonucleoprotein complex (RNP) with proteins Cbf5, Nop10, L7Ae, and Gar1 and guide site-specific conversion of uridine into pseudouridine in cellular RNAs. Uridine 128-135 dyskerin pseudouridine synthase 1 Homo sapiens 62-66 18059286-4 2007 Our structural and complementary fluorescence analyses also indicate that precise placement of the target uridine at the active site requires a conformation of the guide-substrate RNA duplex that is brought about by the previously identified concurrent interaction of the guide RNA with L7Ae and a composite Cbf5-Nop10 surface, and further identify a residue that is critical in this process. Uridine 106-113 dyskerin pseudouridine synthase 1 Homo sapiens 308-312 16427014-3 2006 Cbf5 is the H/ACA protein that catalyzes isomerization of uridine to pseudouridine in target RNAs. Uridine 58-65 dyskerin pseudouridine synthase 1 Homo sapiens 0-4