PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22325350-3	2012	Biochemical and NMR data indicate that hnRNP A1 forms a ternary complex with the U2AF heterodimer on AG-containing/uridine-rich RNAs, while it displaces U2AF from non-AG-containing/uridine-rich RNAs, an activity that requires the glycine-rich domain of hnRNP A1.	Uridine	115-122	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	39-47	
22325350-3	2012	Biochemical and NMR data indicate that hnRNP A1 forms a ternary complex with the U2AF heterodimer on AG-containing/uridine-rich RNAs, while it displaces U2AF from non-AG-containing/uridine-rich RNAs, an activity that requires the glycine-rich domain of hnRNP A1.	Uridine	181-188	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	39-47	
20226755-2	2010	The human UP type 1 (hUP1) is a molecular target for the design of inhibitors intended to boost endogenous uridine levels to rescue normal tissues from the toxicity of fluoropyrimidine nucleoside chemotherapeutic agents, such as capecitabine and 5-fluorouracil.	Uridine	107-114	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	21-25	
20226755-4	2010	These results suggest that hUP1 catalyzes uridine phosphorolysis by a steady-state ordered bi bi kinetic mechanism, in which inorganic phosphate binds first followed by the binding of uridine, and uracil dissociates first, followed by R1P release.	Uridine	42-49	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	27-31	
20226755-4	2010	These results suggest that hUP1 catalyzes uridine phosphorolysis by a steady-state ordered bi bi kinetic mechanism, in which inorganic phosphate binds first followed by the binding of uridine, and uracil dissociates first, followed by R1P release.	Uridine	184-191	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	27-31	
25052233-7	2014	RESULTS: We found that one of the compounds, 6-hydroxy-4-methyl-1H-pyridin-2-one-3-carbonitrile was efficient to promote intestinal mucosa protection and to inhibit the hUP1 enzyme, increasing the uridine levels in the plasma of animals.	Uridine	197-204	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	169-173	
25052233-9	2014	CONCLUSION: Our results bring support to the hUP1 inhibitor strategy as a novel possibility of prevention and treatment of mucositis during the 5-FU chemotherapy, based on the approach of uridine accumulation in plasma and tissues.	Uridine	188-195	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	45-49	
32367200-3	2020	A new synthetic compound, potassium 5-cyano-4-methyl-6-oxo-1,6-dihydropyridine-2-olate (CPBMF65), is a potent inhibitor of the human uridine phosphorylase-1 (hUP1) enzyme, which controls the cell concentration of uridine (Urd).	Uridine	133-140	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	158-162	
32367200-3	2020	A new synthetic compound, potassium 5-cyano-4-methyl-6-oxo-1,6-dihydropyridine-2-olate (CPBMF65), is a potent inhibitor of the human uridine phosphorylase-1 (hUP1) enzyme, which controls the cell concentration of uridine (Urd).	Uridine	222-225	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	158-162