PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1643246-3 1992 The Vmax values were 390 mU/mg of protein, similar to those obtained with methimazole or other substrates for FMO1. Methimazole 74-85 flavin containing dimethylaniline monoxygenase 1 Sus scrofa 110-114 8728504-5 1996 DS3CO was the more effective inhibitor, and at 2 mM it inhibited FMO1 and microsomal-catalyzed oxidation of methimazole (N-methyl-2-mercaptoimidazole) by 80-90%. Methimazole 108-119 flavin containing dimethylaniline monoxygenase 1 Sus scrofa 65-69 9558327-6 1998 In contrast, imipramine inhibits the metabolism of methimazole catalyzed by pig FMO1 at all substrate concentrations. Methimazole 51-62 flavin containing dimethylaniline monoxygenase 1 Sus scrofa 80-84