PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25703523-1 2015 The 2-amine-9H-purine scaffold was identified as a weak bromodomain template and was developed via iterative structure based design into a potent nanomolar ligand for the bromodomain of human BRD9 with small residual micromolar affinity toward the bromodomain of BRD4. 2-amine-9h-purine 4-21 bromodomain containing 4 Homo sapiens 263-267