PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29243607-3 2012 The active components were identified as prenylated flavonols (2-4) that inhibited two related human cholinesterases in a dose-dependent manner, with IC50"s ranging between 0.8 and 3.1muM and between 0.5 and 24.7muM against human acetylcholinesterase (hAChE) and butylcholinesterase (BChE), respectively. Flavonols 52-61 acetylcholinesterase (Cartwright blood group) Homo sapiens 252-257 29243607-5 2012 Flavonols (2-4) showed mixed inhibition kinetics as well as slow and time-dependent reversible inhibition toward hAChE. Flavonols 0-9 acetylcholinesterase (Cartwright blood group) Homo sapiens 113-118 25143139-9 2014 The AChE inhibitions generally increase with the increasing affinities of flavonoids within the class, especially for flavones and flavonols. Flavonols 131-140 acetylcholinesterase (Cartwright blood group) Homo sapiens 4-8 30567381-4 2018 The flavonols 3h, 3i, 3k, 3l and 3p exhibited moderate inhibitory effect against AChE, but significant inhibition against BChE. Flavonols 4-13 acetylcholinesterase (Cartwright blood group) Homo sapiens 81-85