PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9044837-9 1997 In preliminary studies, beta-lapachone and related naphthoquinones are found to be cytotoxic against a panel of drug-sensitive and drug-resistant tumor cell lines, including MDR1-overexpressing cell lines, camptothecin-resistant cell lines, and the atypical multidrug-resistant CEM/V-1 cell line. Naphthoquinones 51-66 ATP binding cassette subfamily B member 1 Homo sapiens 174-178 35462013-0 2022 Naphthoquinone derivatives as P-glycoprotein inducers in inflammatory bowel disease: 2D monolayers, 3D spheroids, and in vivo models. Naphthoquinones 0-14 ATP binding cassette subfamily B member 1 Homo sapiens 30-44 35462013-4 2022 This study aimed to evaluate the potential therapeutic values of naphthoquinone derivatives (NQ-1 - NQ-8) as P-gp modulators to counterbalance intestinal inflammation. Naphthoquinones 65-79 ATP binding cassette subfamily B member 1 Homo sapiens 109-113 26797621-0 2016 Hydroxylated Dimeric Naphthoquinones Increase the Generation of Reactive Oxygen Species, Induce Apoptosis of Acute Myeloid Leukemia Cells and Are Not Substrates of the Multidrug Resistance Proteins ABCB1 and ABCG2. Naphthoquinones 21-36 ATP binding cassette subfamily B member 1 Homo sapiens 198-203