PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7741772-1 1995 58C80 [2-(4-t-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone] is an experimental naphthoquinone antimalarial drug which undergoes extensive alkyl hydroxylation to a single t-butylhydroxy metabolite in man in vivo and also in human liver microsomes, where this is catalysed primarily by a 54 kDa CYP2C9 form of cytochrome P450, P450hB20-27. Naphthoquinones 45-59 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 294-300 8216369-0 1993 Cytochrome P450 2C9 is responsible for hydroxylation of the naphthoquinone antimalarial drug 58C80 in human liver. Naphthoquinones 60-74 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 0-19