PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29185365-2 2018 In this study, we designed and synthesised a series of 2, 3-didithiocarbamate substituted naphthoquinones as PKM2 inhibitors based on the lead compound 3k that we previously reported. Naphthoquinones 90-105 pyruvate kinase M1/2 Homo sapiens 109-113 28688274-3 2017 Here, we report the synthesis and biologic evaluation of novel naphthoquinone derivatives as selective small molecule inhibitors of PKM2. Naphthoquinones 63-77 pyruvate kinase M1/2 Homo sapiens 132-136