PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26862668-6 2016 Moreover, among 1395 cigarette smoke components, naphthoquinones including 9,10-phenaotrenquinone, quinones, benzenediols and alpha, beta-unsaturated carbonyls, were identified as major smoke components that contribute to activating the NRF2/ARE pathway, as indicated by the ARE-reporter assay in BEAS-2B cells. Naphthoquinones 49-64 NFE2 like bZIP transcription factor 2 Homo sapiens 237-241 23054678-7 2013 In addition, incubation with the naphthoquinone derivative resulted in upregulation and nuclear translocation of antioxidant responsive proteins, Nrf2 and Sirt1, which in turn may mediate 1a-directed shift in NSC differentiation. Naphthoquinones 33-47 NFE2 like bZIP transcription factor 2 Homo sapiens 146-150 20695460-11 2010 Western blot analysis showed that both NQ and MCTP significantly induced the Nrf2 mediated stress response pathway despite differences in ROS generation. Naphthoquinones 39-41 NFE2 like bZIP transcription factor 2 Homo sapiens 77-81