PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17656054-1	2008	The composition comprising the highly water-soluble drug meglumine antimoniate (MA) and beta-cyclodextrin (beta-CD) was shown previously to enhance the absorption of Sb by oral route and render MA orally active in a murine model of cutaneous leishmaniasis.	Antimony	166-168	beta-carotene oxygenase 1	Mus musculus	107-114	
17656054-2	2008	This unexpected behaviour was attributed, in part, to the fact that the heating of equimolar mixture of MA and beta-CD (first step of preparation of MA/beta-CD composition) induced the depolymerization of MA from high-molecular weight Sb complexes into 1:1 Sb-meglumine complex, resulting in an enhanced oral bioavailability of Sb.	Antimony	235-237	beta-carotene oxygenase 1	Mus musculus	111-118	
17656054-2	2008	This unexpected behaviour was attributed, in part, to the fact that the heating of equimolar mixture of MA and beta-CD (first step of preparation of MA/beta-CD composition) induced the depolymerization of MA from high-molecular weight Sb complexes into 1:1 Sb-meglumine complex, resulting in an enhanced oral bioavailability of Sb.	Antimony	235-237	beta-carotene oxygenase 1	Mus musculus	152-159	
17656054-2	2008	This unexpected behaviour was attributed, in part, to the fact that the heating of equimolar mixture of MA and beta-CD (first step of preparation of MA/beta-CD composition) induced the depolymerization of MA from high-molecular weight Sb complexes into 1:1 Sb-meglumine complex, resulting in an enhanced oral bioavailability of Sb.	Antimony	257-259	beta-carotene oxygenase 1	Mus musculus	111-118	
17656054-2	2008	This unexpected behaviour was attributed, in part, to the fact that the heating of equimolar mixture of MA and beta-CD (first step of preparation of MA/beta-CD composition) induced the depolymerization of MA from high-molecular weight Sb complexes into 1:1 Sb-meglumine complex, resulting in an enhanced oral bioavailability of Sb.	Antimony	257-259	beta-carotene oxygenase 1	Mus musculus	152-159	
17656054-7	2008	A model is proposed for the mechanisms involved in the enhanced absorption of Sb from the MA/beta-CD composition.	Antimony	78-80	beta-carotene oxygenase 1	Mus musculus	93-100	
16876345-1	2006	It has been previously reported that beta-cyclodextrin (beta-CD) enhances the oral absorption of the pentavalent antimony (Sb) drug, meglumine antimoniate (MA).	Antimony	123-125	beta-carotene oxygenase 1	Mus musculus	56-63	
16876345-5	2006	When MA solution was heated for 48 h at 55 degrees C to mimic the conditions used to prepare MA/beta-CD, MA was found to suffer dissociation, from high molecular weight Sb complexes into species of lower molecular weight.	Antimony	169-171	beta-carotene oxygenase 1	Mus musculus	96-103	
16876345-7	2006	In vitro skin permeation experiments using MA and MA/beta-CD indicated a two-fold increase in the Sb flux for MA/beta-CD.	Antimony	98-100	beta-carotene oxygenase 1	Mus musculus	53-60	
16876345-7	2006	In vitro skin permeation experiments using MA and MA/beta-CD indicated a two-fold increase in the Sb flux for MA/beta-CD.	Antimony	98-100	beta-carotene oxygenase 1	Mus musculus	113-120