PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14634033-1	2004	The disposition of digoxin and the influence of the organic anion transporting polypeptide (Oatp)2 inhibitor rifampicin and the P-glycoprotein (P-gp) inhibitor quinidine on its hepatic disposition were examined in the isolated perfused rat liver.	Rifampin	109-119	solute carrier organic anion transporter family, member 1a4	Rattus norvegicus	92-98	
14634033-9	2004	It is concluded that rifampicin limits the hepatic entrance of digoxin and reduced the hepatic exposure of digoxin to CYP3A by inhibiting the basolateral Oatp2 uptake transport, whereas quinidine increased the hepatic exposure of digoxin to CYP3A by inhibiting the canalicular P-gp transport.	Rifampin	21-31	solute carrier organic anion transporter family, member 1a4	Rattus norvegicus	154-159	
19703346-8	2009	Rifampicin (a potent inhibitor of organic anion transporting polypeptide (Oatp) 2), but not indometacin (a representative inhibitor of organic anion transporter (Oat) 2 and Oatp1) treatment, significantly inhibited the uptake of paclitaxel and TAX-2"-Et.	Rifampin	0-10	solute carrier organic anion transporter family, member 1a4	Rattus norvegicus	34-81	
19703346-9	2009	We characterized the rifampicin-sensitive uptake of paclitaxel and TAX-2"-Et using rat hepatocytes treated with PCN, which dramatically enhances hepatic Oatp2 protein levels.	Rifampin	21-31	solute carrier organic anion transporter family, member 1a4	Rattus norvegicus	153-158	
12085361-2	2002	In rats, rifamycin SV and rifampicin were shown to interfere with hepatic organic anion uptake by inhibition of the organic anion transporting polypeptides Oatp1 and Oatp2.	Rifampin	26-36	solute carrier organic anion transporter family, member 1a4	Rattus norvegicus	166-171	
11883641-5	2002	whereas digoxin, quinine, and rifampicin preferentially inhibited Oatp2 at low concentrations.	Rifampin	30-40	solute carrier organic anion transporter family, member 1a4	Rattus norvegicus	66-71	
10869292-0	2000	Rifamycin SV and rifampicin exhibit differential inhibition of the hepatic rat organic anion transporting polypeptides, Oatp1 and Oatp2.	Rifampin	17-27	solute carrier organic anion transporter family, member 1a4	Rattus norvegicus	130-135	
10869292-6	2000	Rifampicin potently inhibited Oatp2-mediated taurocholate uptake, but did not interfere with Oatp1-mediated taurocholate uptake.	Rifampin	0-10	solute carrier organic anion transporter family, member 1a4	Rattus norvegicus	30-35	
10869292-7	2000	Similar effects of rifamycin SV and rifampicin were found for Oatp1- and Oatp2-mediated estradiol-17beta-glucuronide transport.	Rifampin	36-46	solute carrier organic anion transporter family, member 1a4	Rattus norvegicus	73-78	
10869292-9	2000	These results demonstrate that rifamycin SV and rifampicin exhibit differential inhibition on Oatp1 and Oatp2, and identify rifampicin as a selective Oatp2 inhibitor.	Rifampin	48-58	solute carrier organic anion transporter family, member 1a4	Rattus norvegicus	104-109	
10869292-9	2000	These results demonstrate that rifamycin SV and rifampicin exhibit differential inhibition on Oatp1 and Oatp2, and identify rifampicin as a selective Oatp2 inhibitor.	Rifampin	124-134	solute carrier organic anion transporter family, member 1a4	Rattus norvegicus	150-155