PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30991038-0	2019	Rifampin Induces Expression of P-glycoprotein on the THP1 Cell-Derived Macrophages, Causing Decrease Intramacrophage Concentration of Prothionamide.	Rifampin	0-8	GLI family zinc finger 2	Homo sapiens	53-57	
30991038-3	2019	The present study determined the effect of RIF on MDR1 gene (P-glycoprotein, P-gp) expression in THP1 macrophages and analyzed the intracellular concentration of the anti-TB drug prothionamide in the presence of RIF.	Rifampin	43-46	GLI family zinc finger 2	Homo sapiens	97-101	
31605489-7	2020	Simvastatin, fluvastatin and pravastatin showed the most favorable therapeutic index, and enhanced the anti-tubercular activity of the first-line drugs isoniazid, rifampin and pyrazinamide in THP-1 cells.	Rifampin	163-171	GLI family zinc finger 2	Homo sapiens	192-197	
26214306-4	2015	Intracellular and secreted proteomes from activated THP-1 cells infected with the Mtb H37Rv strain (MOI = 1) and treated with isoniazid and rifampicin for 1 day (infection stage) and 5 days (clearance stage) were analyzed.	Rifampin	140-150	GLI family zinc finger 2	Homo sapiens	52-57	
18727801-5	2008	Extracellular (broth) and intracellular (THP-1 macrophages) activities of rifampicin, linezolid and fusidic acid at C(max), and of vancomycin, daptomycin, quinupristin-dalfopristin and oritavancin over a wide range of extracellular concentrations (with pharmacological modelling to determine E(max)), were measured at 24 h. Increases in vancomycin MICs correlated with increased drug binding, and decreased cell wall turnover and detergent-induced autolysis.	Rifampin	74-84	GLI family zinc finger 2	Homo sapiens	41-46	
15883178-10	2005	In particular, rifampicin and the fluoroquinolones were the most active compounds, both in extracellular medium and in THP-1 cells.	Rifampin	15-25	GLI family zinc finger 2	Homo sapiens	119-124