PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21555507-6	2011	IL-6 suppressed induction of CYP1A2 enzyme activity by omeprazole and CYP3A4 enzyme activity by rifampicin but only at supraphysiological concentrations of IL-6.	Rifampin	96-106	interleukin 6	Homo sapiens	0-4	
15332711-3	2004	Secretion of IL-1beta and TNF-a were significantly inhibited (P<0.002) whereas secretion of IL-6 and IL-10 were significantly increased (P<0.003) by rifampicin treated mononuclear cells.	Rifampin	155-165	interleukin 6	Homo sapiens	95-99	
35048417-6	2022	Analysis of cell culture medium of rifampicin treated HS explants revealed an anti-inflammatory effect of rifampicin that significantly inhibiting interleukin (IL)-1beta, IL-6, IL-8, IL-10, and tumour necrosis factor (TNF) -alpha production.	Rifampin	35-45	interleukin 6	Homo sapiens	171-175	
10924340-4	2000	In parallel, IL-6 decreases both rifampicin- and phenobarbital-mediated induction of CYP2B6, CYP2C8, CYP2C9, and CYP3A4.	Rifampin	33-43	interleukin 6	Homo sapiens	13-17	
35048417-6	2022	Analysis of cell culture medium of rifampicin treated HS explants revealed an anti-inflammatory effect of rifampicin that significantly inhibiting interleukin (IL)-1beta, IL-6, IL-8, IL-10, and tumour necrosis factor (TNF) -alpha production.	Rifampin	106-116	interleukin 6	Homo sapiens	171-175	
33970450-7	2021	RESULTS: Based on the findings, Rifampicin and Letermovir appeared as the most promising drug showing a very good binding affinity with the main protease of SARS-CoV-2 and TNF-alpha, IL-6, and IL-1beta.	Rifampin	32-42	interleukin 6	Homo sapiens	183-187	
31349736-3	2019	Pretreatments with Rif and RifQ reduced the secretion of prototypical inflammatory cytokines (TNF- , IL-6) and the burst of oxidative stress in microglial cells activated with alphaS fibrillary aggregates.	Rifampin	19-22	interleukin 6	Homo sapiens	101-105	
31648047-5	2020	We found that rifampicin pretreatment suppressed the gene expression of IL-1beta and IL-6 via inhibiting activation of JNK after rotenone induction, but the anti-inflammatory effect of rifampicin was reversed by chloroquine.	Rifampin	14-24	interleukin 6	Homo sapiens	85-89