PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20237659-3	2010	Functionalised enolates provide a direct entry to C-3 functionalised lactams, as exemplified by total syntheses of (-)-aphanorphine, (+)-laccarin and (-)-paroxetine.	Lactams	69-76	complement C3	Homo sapiens	50-53	
31965920-5	2019	OBJECTIVE: The present review aims to highlight recent advancement made in C-3 functionalization of beta - lactams.	Lactams	107-114	complement C3	Homo sapiens	75-78	
18991377-7	2008	Reaction of NCPs 12 with silver(I) acetate gave silver(III) derivatives 21a and 21b where an oxidation had occurred at C-3 to afford a lactam unit.	Lactams	135-141	complement C3	Homo sapiens	119-122	
8352545-2	1993	In particular, we discuss the antitumor activity of the esters of homo-aza steroids in which the p-N,N-bis(2-chloroethyl)aminophenoxyacetic acid is linked to the C-3 or C-17 position, while the lactam nucleus is linked to the D or A ring of the modified steroid respectively.	Lactams	194-200	complement C3	Homo sapiens	162-165	
25338052-0	2014	Synthesis of lactams by isomerization of oxindoles substituted at C-3 by an omega-amino chain.	Lactams	13-20	complement C3	Homo sapiens	66-69	
25338052-1	2014	Oxindoles substituted at N-1 by electron-withdrawing groups and at C-3 by omega-amino chains of various lengths undergo mild and easy isomerization to new 5- to 12-membered lactams in good yields (30-96%).	Lactams	173-180	complement C3	Homo sapiens	67-70