PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8127415-0 1993 A fast protein liquid chromatography (FPLC) method for study of thyrotropin-releasing hormone (TRH) and its metabolite histidyl-proline diketopiperazine (CHP) in human blood: degradation in liver and pancreatic diseases. histidyl-proline diketopiperazine 119-152 calcineurin like EF-hand protein 1 Homo sapiens 154-157 8127415-1 1993 We have developed a convenient method combining fast protein liquid chromatography (FPLC) with sensitive radioimmunoassay (RIA) for thyrotropin-releasing hormone (TRH) to separate and identify TRH and its metabolite histidyl-proline diketopiperazine (CHP) and applied this to study inactivation of TRH by blood extracts from patients with liver cirrhosis (LC) and acute edematous pancreatitis (AP). histidyl-proline diketopiperazine 216-249 calcineurin like EF-hand protein 1 Homo sapiens 251-254