PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17450230-6 2007 We found three intronic polymorphisms in AS3MT (G12390C, C14215T, and G35991A) associated with a lower percentage of MMA (%MMA) and a higher percentage of DMA (%DMA) in urine. dma 155-158 arsenite methyltransferase Homo sapiens 41-46 17450230-6 2007 We found three intronic polymorphisms in AS3MT (G12390C, C14215T, and G35991A) associated with a lower percentage of MMA (%MMA) and a higher percentage of DMA (%DMA) in urine. dma 161-164 arsenite methyltransferase Homo sapiens 41-46 30376134-5 2018 Patients with the AS3MT rs3740390 TC or TT genotype, compared with rs3740390 CC genotype, had significantly higher levels of DMA%, SMI and significantly lower levels of ALT and AST. dma 125-128 arsenite methyltransferase Homo sapiens 18-23 34730462-4 2021 AS3MT polymorphisms are associated with the proportions of monomethylarsenic acid (MMA) and dimethylarsenic acid (DMA) in urine as well as the incidence of cancer. dma 114-117 arsenite methyltransferase Homo sapiens 0-5 30893314-11 2019 In our study population, FTCD and AS3MT SNPs together explain ~10% of the variation in DMA% and support a causal effect of arsenic metabolism efficiency on arsenic toxicity (i.e., skin lesions). dma 87-90 arsenite methyltransferase Homo sapiens 34-39 28640505-2 2017 Arsenic (+3) methyltransferase (AS3MT) is the primary enzyme involved in arsenic metabolism, and we previously demonstrated in vitro that N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) also methylates the toxic inorganic arsenic (iAs) metabolite, monomethylarsonous acid (MMA), to the less toxic dimethylarsonic acid (DMA). dma 325-328 arsenite methyltransferase Homo sapiens 32-37 28640505-7 2017 For example, compared to wildtypes, individuals carrying minor alleles in AS3MT rs3740393 had lower %MMA (mean difference = -1.9%, 95% CI: -3.3, -0.4), higher %DMA (mean difference = 4.0%, 95% CI: 1.5, 6.5), and lower odds ratios for bladder (OR = 0.3; 95% CI: 0.1-0.6) and lung cancer (OR = 0.6; 95% CI: 0.2-1.1). dma 160-163 arsenite methyltransferase Homo sapiens 74-79