PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32592701-7 2020 Mechanistic studies revealed that lycopene treatment (20 mg/kg, 12 days) could suppress the SPS-induced increase in levels of interleukin-6 (IL-6), IL-1beta, tumor necrosis factor-alpha (TNF-alpha), and nitrite in the hippocampus and prefrontal cortex in mice, as well as the increased markers that indicate high levels of oxido-nitrosative stress in the hippocampus and prefrontal cortex in SPS mice. Lycopene 34-42 tumor necrosis factor Mus musculus 158-185 33987329-5 2021 Lycopene inhibited F4/80+ macrophage and Ly6G+ neutrophil accumulation, which further decreased the levels of tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), and interleukin 6 (IL-6). Lycopene 0-8 tumor necrosis factor Mus musculus 110-137 33987329-5 2021 Lycopene inhibited F4/80+ macrophage and Ly6G+ neutrophil accumulation, which further decreased the levels of tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), and interleukin 6 (IL-6). Lycopene 0-8 tumor necrosis factor Mus musculus 139-148 32592701-7 2020 Mechanistic studies revealed that lycopene treatment (20 mg/kg, 12 days) could suppress the SPS-induced increase in levels of interleukin-6 (IL-6), IL-1beta, tumor necrosis factor-alpha (TNF-alpha), and nitrite in the hippocampus and prefrontal cortex in mice, as well as the increased markers that indicate high levels of oxido-nitrosative stress in the hippocampus and prefrontal cortex in SPS mice. Lycopene 34-42 tumor necrosis factor Mus musculus 187-196 25689917-9 2015 The immunohistochemical experiment exhibited that lycopene intake contributed to attenuation of nuclear factor-kappa B (NF-kappaB) and tumor necrosis factor alpha (TNF-alpha) expressions in kidney tissue. Lycopene 50-58 tumor necrosis factor Mus musculus 135-162 30198495-5 2018 The levels of inflammatory factors, including interleukin-1 (IL1), IL6, IL8, and tumor necrosis factor-alpha (TNF-alpha), in lycopene-treated cells were also reduced by lycopene treatment. Lycopene 125-133 tumor necrosis factor Mus musculus 81-108 30198495-5 2018 The levels of inflammatory factors, including interleukin-1 (IL1), IL6, IL8, and tumor necrosis factor-alpha (TNF-alpha), in lycopene-treated cells were also reduced by lycopene treatment. Lycopene 125-133 tumor necrosis factor Mus musculus 110-119 30198495-5 2018 The levels of inflammatory factors, including interleukin-1 (IL1), IL6, IL8, and tumor necrosis factor-alpha (TNF-alpha), in lycopene-treated cells were also reduced by lycopene treatment. Lycopene 169-177 tumor necrosis factor Mus musculus 81-108 29475907-8 2018 LPS-stimulated Cox2, Nos2 and Tnfa gene expression was inhibited by 50 muM beta-carotene and lycopene, and by 0.5-1% TBB. Lycopene 93-101 tumor necrosis factor Mus musculus 30-34 28651168-14 2017 There was an increase in the levels of tumor necrosis factor-alpha, interferon-gamma and interleukin-10 after exposure to CS, and these effects were suppressed by both doses of lycopene. Lycopene 177-185 tumor necrosis factor Mus musculus 39-66 27357536-10 2016 The expression of the proinflammatory factors TNF-alpha and NF-kB increased markedly 48 h after SCI, and their upregulation was significantly attenuated by lycopene treatment. Lycopene 156-164 tumor necrosis factor Mus musculus 46-55 30198495-5 2018 The levels of inflammatory factors, including interleukin-1 (IL1), IL6, IL8, and tumor necrosis factor-alpha (TNF-alpha), in lycopene-treated cells were also reduced by lycopene treatment. Lycopene 169-177 tumor necrosis factor Mus musculus 110-119 28472825-5 2017 We found that Lycopene notably prevented the increase of IL-1beta, TNFalpha and CRP levels in mice fed HFD. Lycopene 14-22 tumor necrosis factor Mus musculus 67-75 25689917-9 2015 The immunohistochemical experiment exhibited that lycopene intake contributed to attenuation of nuclear factor-kappa B (NF-kappaB) and tumor necrosis factor alpha (TNF-alpha) expressions in kidney tissue. Lycopene 50-58 tumor necrosis factor Mus musculus 164-173 25323011-9 2015 Lycopene reduced the expression of TGF-beta1, collagen I, collagen III, TNF-alpha, IL-1beta, caspase-3, -8 and -9 and inhibited the activation of the NF-kappaB signaling pathway. Lycopene 0-8 tumor necrosis factor Mus musculus 72-81 19693648-3 2010 RESULTS: Lycopene inhibited LPS-induced production of nitric oxide (NO) and interleukin-6 (IL-6) with decreased mRNAs of inducible nitric oxide synthase and IL-6 but had no effect on TNF-alpha. Lycopene 9-17 tumor necrosis factor Mus musculus 183-192 18055235-3 2008 The aim of the present study was to explore the antinociceptive effect of lycopene and its effect on tumour necrosis factor-alpha (TNF-alpha) and nitric oxide (NO) release in streptozotocin induced diabetic mice. Lycopene 74-82 tumor necrosis factor Mus musculus 131-140 18055235-7 2008 Lycopene also inhibited the TNF-alpha and NO release in a dose dependent manner. Lycopene 0-8 tumor necrosis factor Mus musculus 28-37 18055235-8 2008 These results indicate an antinociceptive activity of lycopene possibly through its inhibitory action on NO and TNF-alpha release and point towards its potential to attenuate diabetic neuropathic pain. Lycopene 54-62 tumor necrosis factor Mus musculus 112-121