PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27631138-5	2016	Results showed that Sarcandra glabra and lycopene could significantly ameliorate LPS-induced histopathological injuries, improve the anti-oxidative activities of rats, decrease the levels of TNF-alpha and IL-6, suppress the activations of MAPK and transcription factor NF-kappaB and reverse the disturbed metabolism towards the normal status.	Lycopene	41-49	interleukin 6	Rattus norvegicus	205-209	
34294819-8	2021	Furthermore, upregulated expressions of Interleukin-1beta, Interleukin-6, and NF-kB-p65 in the PA control were attenuated, while decreased Interleukine-10 expression was upregulated due to lycopene treatment.	Lycopene	189-197	interleukin 6	Rattus norvegicus	59-72	
23632237-0	2013	Lycopene supplementation modulates plasma concentrations and epididymal adipose tissue mRNA of leptin, resistin and IL-6 in diet-induced obese rats.	Lycopene	0-8	interleukin 6	Rattus norvegicus	116-120	
23632237-9	2013	Although lycopene supplementation did not affect BW or adiposity, it significantly decreased leptin, resistin and IL-6 gene expression in epididymal adipose tissue and plasma concentrations.	Lycopene	9-17	interleukin 6	Rattus norvegicus	114-118	
23632237-11	2013	Lycopene affects adipokines by reducing leptin, resistin and plasma IL-6 levels.	Lycopene	0-8	interleukin 6	Rattus norvegicus	68-72	
25888837-6	2015	Lycopene also modified the levels of immunoregulatory cytokines (IL- 1beta and IL-6) favourably.	Lycopene	0-8	interleukin 6	Rattus norvegicus	79-83	
25410533-4	2015	The serum levels of tumor necrosis factor-alpha, interleukin-6, macrophage inflammatory protein-1alpha, and monocyte chemotactic protein-1 were decreased by lycopene.	Lycopene	157-165	interleukin 6	Rattus norvegicus	49-62	
34018317-6	2021	Under high-fat diet, lycopene reduced the levels of IL-17, IL-6 and TNF-alpha in placenta (P<0.05) through the IL-17 pathway.	Lycopene	21-29	interleukin 6	Rattus norvegicus	59-63	
32290942-10	2020	Compared with the model group, liver weight, liver index, levels of serum ALT, TG, FBG, IL-6 and IL-1beta were significantly lower in the 20, 60 mg/kg lycopene intervention groups(P<0.	Lycopene	151-159	interleukin 6	Rattus norvegicus	88-92	
31161929-13	2018	When comparing NC and NL groups, negative effects were observed in the group given lycopene in terms of MLI, PCNA, apoptosis, and IL-6 (all parameters, p = 0.001).	Lycopene	83-91	interleukin 6	Rattus norvegicus	130-134	
34914324-7	2021	The expressions of the inflammatory factors IL-1beta, IL-2, IL-6, TNFalpha, MCP1 and MIP-1alpha in the prostate tissue were all dramatically decreased in the quercetin, curcumin, lycopene and combination therapy groups compared with those in the normal controls (P < 0.01), even lower in the combination therapy group than in the quercetin, curcumin and lycopene groups (P < 0.05).	Lycopene	179-187	interleukin 6	Rattus norvegicus	60-64	
34914324-7	2021	The expressions of the inflammatory factors IL-1beta, IL-2, IL-6, TNFalpha, MCP1 and MIP-1alpha in the prostate tissue were all dramatically decreased in the quercetin, curcumin, lycopene and combination therapy groups compared with those in the normal controls (P < 0.01), even lower in the combination therapy group than in the quercetin, curcumin and lycopene groups (P < 0.05).	Lycopene	354-362	interleukin 6	Rattus norvegicus	60-64	
33672594-6	2021	This study aimed to investigate whether lycopene inhibits the EtOH/POA-induced increase in ROS production, zymogen activation, and expression of the inflammatory cytokine IL-6 in EtOH/POA-stimulated pancreatic acinar AR42J cells.	Lycopene	40-48	interleukin 6	Rattus norvegicus	171-175	
33672594-7	2021	EtOH/POA increased the ROS levels, NADPH oxidase and NF-kappaB activities, zymogen activation, IL-6 expression, and mitochondrial dysfunction, which were inhibited by lycopene.	Lycopene	167-175	interleukin 6	Rattus norvegicus	95-99	
33672594-9	2021	Therefore, lycopene inhibits EtOH/POA-induced mitochondrial dysfunction, zymogen activation, and IL-6 expression by suppressing NADPH oxidase-mediated ROS production in pancreatic acinar cells.	Lycopene	11-19	interleukin 6	Rattus norvegicus	97-101