PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20030056-1	2009	OBJECTIVE: Lycopene epsilon cyclase (LCYE) is the key enzyme in the lutein synthesis pathway and catalyses linear lycopene to form cyclic epsilon-carotene, a presucursor of lutein.	Lycopene	114-122	uncharacterized protein	Chlamydomonas reinhardtii	37-41	
20030056-6	2009	Furthermore, the E. coli strain containing the pAC-LYC plasmid which could accumulate lycopene was used for the functional confirmation of LCYE from C. protothecoides CS-41.	Lycopene	86-94	uncharacterized protein	Chlamydomonas reinhardtii	139-143	
33528746-2	2021	In the microalgal carotenoid biosynthetic pathway, lycopene is converted either into beta-carotene by lycopene beta-cyclase or into alpha-carotene by lycopene epsilon-cyclase (LCYE) and lycopene beta-cyclase.	Lycopene	51-59	uncharacterized protein	Chlamydomonas reinhardtii	150-174	
33528746-2	2021	In the microalgal carotenoid biosynthetic pathway, lycopene is converted either into beta-carotene by lycopene beta-cyclase or into alpha-carotene by lycopene epsilon-cyclase (LCYE) and lycopene beta-cyclase.	Lycopene	51-59	uncharacterized protein	Chlamydomonas reinhardtii	176-180	
33528746-3	2021	In this study, we overexpressed the LCYE gene in C. reinhardtii to estimate its effect on lycopene metabolism and lutein production.	Lycopene	90-98	uncharacterized protein	Chlamydomonas reinhardtii	36-40	
33528746-6	2021	These results suggest that LCYE overexpression enhances the conversion of lycopene to alpha-carotene, which in turn improves lutein productivity.	Lycopene	74-82	uncharacterized protein	Chlamydomonas reinhardtii	27-31	
33528746-8	2021	Considering that the inhibition of the lycopene cyclization steps often induces higher expression in genes upstream of metabolic branches, this result implies that the redirection from beta-carotene to alpha-carotene by LCYE overexpression might also enhance upstream gene expression, thereby leading to auxiliary beta-carotene production.	Lycopene	39-47	uncharacterized protein	Chlamydomonas reinhardtii	220-224